1b Psychosis Flashcards

1
Q

What is psychosis?

A

difficulty perceiving and interpreting reality (i.e. failure of reality testing)

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2
Q

What are some examples of psychotic disorders?

A

Bipolar
Schizoaffective disorder
depression
delusional disorder

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3
Q

What are the three symptom domains in psychosis?

A

Positive symptoms
Negative symptoms
disorganisation

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4
Q

What are the positive symptoms of psychosis?

A

Hallucinations
Delusions

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5
Q

What is a delusion?

A

A fixed, false belief not in keeping with social/cultural norms

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6
Q

What are the negative symptoms of psychosis?

A

Alogia
Anhedonia
Affective flattening
Avolution/apathy

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7
Q

What is alogia?

A

Paucity/poverty of speech, little content
Slow to respond

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8
Q

What is affective flattening?

A

Unchanging facial expressions
Few expressive gestures
Poor eye contact
Lack of vocal intonations
Limited emotional range

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9
Q

What is avolution?

A

Poor self-care
Lack of drive/persistence at work/education
Lack of motivation

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10
Q

What are the types of disorganisation symptoms?

A

Bizarre behaviour
Formal thought disorder

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11
Q

What is formal thought disorder?

A

Lack of logical connection between thoughts

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12
Q

What are the environmental risk factors for psychosis?

A

Drug use, especially cannabis
Prenatal/birth complications
Maternal infections
Migrant status
Socioeconomic deprivation
Childhood trauma

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13
Q

What neurotransmitter is most implicated in antipsychotic medication?

A

Dopamine

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14
Q

What causes the positive symptoms of psychosis?

A

Increased dopamine activity in mesolimbic dopamine system implicated in causing positive symptoms of psychosis

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15
Q

What makes something a ‘typical’ versus an ‘atypical’ antipsychotic?

A

Typical antipsychotics are older agents and have an increased risk of causing EPSE

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16
Q

What is EPSE?

A

Extra pyramidal side effects

17
Q

What are some EPSE?

A

Parkinsonism
Acute dystonic reactions
Tardive dyskinesia
Akathisia

18
Q

What is Akathisia?

A

Inability to stall still

19
Q

What are the side effects of antipsychotics?

A

Agranulocytosis
neutropenia
Increased appetite
Weight gain
Constipation
Increased prolactin as release suppressed by dopamine