1b Dialysis and Kidney Transplant Flashcards
Differentiate between AKI and CKD?
AKI —>present before creatinine gets very bad; often normal sized kidneys; acutely unwell
CKD–> present with higher creatinine usually due to secondary trigger (eg.infection);often small kidneys; Patients are often asymptomatic and CKD is discovered incidentally on routine screening or workup of unrelated diseases
What can cause AKI?
NSAIDS can cause tubulointerstitial nephritis
ACEi predispose to AKI
Infection—>sepsis—>hypotension—>AKI
Dehydration
Hypovolemic states like an acute hemorrhage, gastrointestinal losses- like with diarrhea and vomiting, renal losses
What can cause CKD?
Diabetes
Lupus
Hypertension
Infection
Systemic diseases
Long term use of NSAIDs
What treatment should be considered for a patient presenting with AKI or CKD and hyperkalaemia?
Treatment relies on urgent dialysis or a temporizing measures until dialysis can be arranged.
Adress hyperkalaemia
ECG changes?
Urinating? if yes—>diuretics, IV bicarbonate, IV calcium gluconate, IV insulin to correct hyperkalaemia
Potassium binders
Dialysis
What are the two different types of dialysis?
Haemodialysis and Peritoneal dialysis
What is the dialysate in dialysis?
Dialysate isa solution of pure water, electrolytes and salts, such as bicarbonate and sodium.The purpose of dialysate is to pull toxins from the blood into the dialysate
How does peritoneal dialysis work?
The inside lining of your own belly acts as a natural filter.
You will need a minor operation to place a catheter in your abdomen (belly) for access.
During the treatment, the peritoneal cavity is slowly filled with dialysate through the catheter. The blood stays in the arteries and veins that line the peritoneal cavity. Extra fluid and waste products are drawn out of the blood and into the dialysate.
What are the benefits of haemodialysis?
Allows for 4 treatment free days per week.
What are the disadvantages of haemodialysis?
- need to visit center
- strict dietary constraints
- Needs arteriovenous fistula for access
What are the advantages of peritoneal dialysis?
- Done at home
- less constraint on food and water
- Travel is much easier
What are the disadvantages of peritoneal dialysis?
Normally 7 days a week
chance of infection due to catheter or peritonitis
What are the three factors to consider when doing a live donor kidney transplant, to do witht he kidney match?
Blood type compatibility
HLA typing
Serum cross matching
What are factors to consider when doing a live kidney donor transplant?
Age
Comorbidities
Kidney Match
Future Pregnancies
Mental Health History
Financial Stability
Family Historuy
what happens to the native kidneys in kidney transplantation?
They are left in the abdomen if there is space
What are the food and water recommendations post transplant?
Low salt and sugar diet
No raw eggs or meat
Regular fluid intake
Not food items which can interact with tacrolimus (the immunosuppresant)