19-2: Lymphoid organs Flashcards
lymphoid organs
fight infection, provide resistance to disease
aggregates of lymphatic tissue in the body; all made of a type of reticular connective tissue and consist of two main types of cells
What two main types of cells make up lymphoid organs?
lymphocytes and macrophages
lymphocytes
main warriors of the immune system, arising in red bone marrow. Develop into T cells or B cells
T cells
manage immune response; directly attach and destroy foreign cells
B cells
develop into plasma cells which in turn secrete antibodies that immobilize the antigen until it can be phagocytized
macrophages
large cells that phagocytize foreign substanes and help to activate T cells (initiating the immune response)
What are examples of lymphoid organs?
thymus, spleen, tonsils, Peyer’s patches (on intestines), appendix
How are lymphoid organs different from lymph nodes?
They do not filter the lymph of debris, pathogens, or foreign cells
spleen
largest lymphoid organ, located in LUQ just inferior to diaphragm
What are the functions of the spleen?
- proliferation of lymphocytes during the immune response
- cleanses blood of old/defective blood cells, debris, foreign matter, bacteria, viruses, and toxins (NOT the lymph)
- stores breakdown products of RBCs for later reuse
- site of erythrocyte production in the fetus
- stores blood platelets
splenestomy
removal of the spleen due to a rupture (usually a direct blow, bursting the thin capsule); splenic artery is tied off.
Which organs take over the spleen’s functions if it is removed?
liver and bone marrow
Thymus
bi-lobed gland in lower neck/upper chest that is most important in childhood
Which is the only lymphoid organ that does not directly fight antigens?
Thymus (no B cells)
What is the function of the thymus?
T-lymphocyte maturation - produces hormones to enable T-lymphocytes to function against specific pathogens during the immune response