18.7.2013 Flashcards
Na+ requirement for a normal person
75-175 mEq/D
Amount of glucose that must be taken daily to prevent starvation ketosis
100-150g/d
K+ requirement for a normal person
20-60 mEq/D
Amount of glucose in 5D
5g/L
Osmolality of 5D and ringer lactate
5D- 278
RL-274
Renal causes of hypovolemia
Diuresis
Salt losing nephropathy
Mineralocorticoid deficit
Removal of obstruction in obstructive nephropathy
Non renal causes of hypovolemia
GIT vomiting Excess nasogastric suction Fistula Diarrhoea Respiratory loss Burns Third spacing Hemorrhage
Signs of hypovolemia
Low JVP
Postural hypotension
Postural tachycardia
Absence of axillary sweat
Urine sodium in hypovolemia
Less than 15mEq
FeNa less than 1%
Role of urine chloride measurement in hypovolemia
Urine Cl less than 20mEq
In metabolic alkalosis associated with hypovolemia,urine sodium excretion may be increased
Lab values in hypovolemia
Decreased urine Na and Cl
Increased urine osmolality
Increased serum bicarbonate
Increased HCT and serum albumin
Presentation of hypervolemia
Weight gain(earliest indication of Na retention) Edema Effusions Elevated JVP Hepatojugular reflex S3 Rales Elevated BP
Diuretics and free water clearance
Thiazides decrease positive free water clearance
Loop diuretics increase positive free water clearance
Diuretics useful in decreased renal perfusion and impaired tubular function
Aldosterone antagonists
Pseudohyponatremia
Increased plasma proteins and lipids