18: Micro-circulation Flashcards
Average velocity of blood through capillaries dependent on
arteriole constriction
Venule pressure
Endothelial and local factors
Diffusion of substances in blood
flow limited
increased flow= increased transfer
Transcapillary efflux rate
= Flow x (arterial concentration - venous concentration)
Factors driving fluid flitration
Hydrostatic pressure within capillary
Interstitial protein oncotic pressure
Factors driving fluid reabsorption
interstitial fluid pressure (negligible unless edema)
Plasma protein oncotic pressure
How does pressure change through the capillaries
Beginning: filtration
End: Reabsorption
Purpose of lymph system
Maintain low interstitial hydrostatic and oncotic pressures
valves for unidirectional flow
Free flow of large molecules
Increased arteriolar resistance
Increased reabsorption
Increased venous resistance
increased filtration
Size of junctions in the brain
Small
Size of junctions in the liver
Large