17.5.2022

Question 1

Anaemia of inflammatory disease is characterized by:

Answer 1

Low serum iron, low total iron binding capacity, high bone marrow iron, high percentage transferrin saturation

Question 2

What are erythrocyte ghosts?

Answer 2

They are pale-staining empty cells on the blood film

Question 3

What is diagnostic importance of RDW?

Answer 3

It describes the variability in red blood cell size and is expressed in %

Question 4

What is prevalence?

Answer 4

It is an estimate of the frequency of a disease in a population at a point in time

Question 5

Acute leukaemia occurs:

Answer 5

when neoplastic transformation occurs at the stem cell/comitted blast stage and the malignant cells have little differential potential, proliferate rapidly and in uncontrolled manner. The clinical course is rapid and clinical signs are severe. Normal blood cell production is significantly reduced.

Question 6

Disseminated intravascular coagulation is characterized by augmentation of normal clotting mechanisms which results in depletion of coagulation factors, deposition of fibrin clots in the microvasculature, the second activation of fibrinolytic mechanisms with the production of fibrin-degradation products (FDP) which have anticoagulant properties. There is pathophysiological paradox -…………. in the presence of haemorrhage:

Answer 6

thrombosis

Question 7

True or false: Punctate reticulocytes are more mature than aggregate reticulocytes in cat

Answer 7

True

Question 8

The longest life span of red blood cells is in:

Answer 8

reptiles

Question 9

Normal or low PCV with high plasma protein:

Answer 9

Hyperglobulinemia

Question 10

What is polychromatic cell?

Answer 10

Young red blood cell

Question 11

A major blood forming organ in the bony fish is:

Answer 11

the kidney

Question 12

Von Willebrand factor is needed for:

Answer 12

• adherence of the platelet to the subendothelial surface of an injured vessel
• contributes to platelet aggregation.
• It stabilizes coagulation factor VIII.

Question 13

What are schistocytes and what is their diagnostic importance?

Answer 13

RBC fragments: vascular neoplasms (e.g., haemangiosarcoma), DIC, iron deficiency

Question 14

True or false: In a degenerative left shift there is a low or normal RBC count and band neutrophils exceeds mature neutrophils

Answer 14

True

Question 15

Nucleated platelets (thrombocytes) are not present in the blood films of:

Answer 15

mammals