17 - Inherited change Flashcards

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1
Q

Define an allele.

A

One of a number of alternative forms of a gene.

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2
Q

Define a gene.

A

A section of DNA on a chromosome coding for one or more polypeptides.

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3
Q

Define a dominant allele.

A

An allele always expressed in the phenotype of an organism.

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4
Q

Define a recessive allele.

A

The effect of the allele is apparent in the phenotype of a diploid organism only in the presence of another identical allele.

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5
Q

Define heterozygous.

A

The condition where the alleles of a particular gene are different.

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6
Q

Define homozygous.

A

The condition where the alleles of a particular gene are identical.

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7
Q

Define phenotype.

A

Expression of the genetic constitution and its interaction with the environment.

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8
Q

Define genotype.

A

The genetic composition of an organism.

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9
Q

Define a chromosome.

A

A thread-like structure made of protein and DNA by which hereditary information is physically passed from one generation to the next.

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10
Q

Define an autosome.

A

A chromosome which is not a sex chromosome.

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11
Q

What is a locus? (inheritance)

A

The position of a gene on a particular DNA molecule.

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12
Q

What is it called when two alleles are expressed in the phenotype?

A

Codominant

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13
Q

What is the F1 generation?

A

Name given to the first generation resulting from a homozygous dominant individual being crossed with a homozygous recessive individual.

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13
Q

What sex chromosomes does a male human have?

A

XY

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14
Q

Is the X or Y chromosome larger?

A

X

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15
Q

What is autosomal linkage?

A

When genes appear on the same, non-sex chromosome. (No independent assortment)

16
Q

What is epistasis?

A

When the allele of one gene affects or masks the expression of another in the phenotype.

17
Q

How is the degrees of freedom determined?

A

Number of classes - 1

18
Q

Give four causes of genetic variation.

A

Crossing over
Independent segregation
Random fertilisation
Mutation

19
Q

In genetic crosses, the observed phenotypic ratios obtained are not often the same as expected. Why (5 reasons)

A

Small sample size
Random fertilisation of gametes
Linked genes
Epistasis
Lethal genotypes

20
Q

What is meant by codominant alleles?

A

Both alleles expressed in phenotype

21
Q

Two genes are linked. Explain what this means.

A

On same chromosome

22
Q

Which statistical test should the scientist use to determine whether his observed results were significantly different from the expected result? Why? (2)

A

Chi squared
Categorical data