17 - Chronic DM complications Flashcards

1
Q

polyol pathway and which DM complication it most contributes to

A

in hyperglycemia, inc levels of aldose reductase > converts glucose to sorbitol > can’t be metabolized and disrupts osmotic balance

most important in retinopathy

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2
Q

how long does it take to get retinopathy w/ poor glycemic control in DM?

A

5 yrs from dx

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3
Q

which type of DM has more problems w/ nephropathy?

A

type 1

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4
Q

range for microalbuminuria

A

30-300 mg/d

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5
Q

MC chronic complication of DM

A

neuropathy

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6
Q

neuropathy finding that most closely correlates w/ CV risk in DM pt

A

erectile dysfunction

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7
Q

4 features of diabetic dyslipidemia

A

inc fraction of small dense LDL
dec HDL
hyperTGs
postprandial lipemia

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8
Q

risk of taking multiple types of cholesterol lowering meds

A

rhabdomyolysis

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