生理17 Flashcards

1
Q

NK cell具吞噬能力嗎?

A

不具

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2
Q

NK cell攻擊的目標是?

A

受感染的細胞

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3
Q

NK cell如何攻擊目標細胞

A

分泌granzyme 和perfornin 造成細胞膜破損

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4
Q

可產生perforin和granzyme的有哪兩個細胞

A

NK cell

Tc cell

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5
Q

TLR3偵測?

A

雙股RNA病毒

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6
Q

TLR4偵測?

A

細菌的脂多糖(LPS)

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7
Q

TLR5偵測?

A

細菌的鞭毛(鞭毛素)

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8
Q

TLR9偵測

A

未被甲基化的CpG DNA

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9
Q

淋巴液與血漿的差異?兩點

A

淋巴液蛋白質含量較低

淋巴液多了白血球

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10
Q

初級淋巴器官有哪兩個

A

骨髓

胸線

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11
Q

次級淋巴器官有哪三個

A

脾臟 淋巴結 扁桃體

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12
Q

淋巴球在哪兩處成熟

A

胸腺和骨髓

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13
Q

抗原主要由什麼組成

A

大分子多醣類(主)

蛋白質

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14
Q

三個抗原呈現細胞的例子

A

巨噬細胞
B cell
樹突細胞

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15
Q

被活化的抗原呈現細胞稱作

A

co stimulators molecule

輔刺激因子

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16
Q

免疫球蛋白分子IgM IgG IgA IgD IgE由抗體的什麼部位決定?

A

由抗體的heavy chain恆定區決定

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17
Q

什麼酵素可以用來切Fab和Fc

A

Papain木瓜酶

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18
Q

內生性熱源有哪三個

A

TNF
IL-1
IL-6

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19
Q

體溫調控中樞在哪

A

下視丘

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20
Q

體溫調控器官在哪

A

皮膚

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21
Q

細胞素有哪三個

A

間白素
干擾素
腫瘤壞死因子TNF

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22
Q

TNF alpha由什麼分泌 是幹嘛的?

A

由macrophage分泌 殺腫瘤的

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23
Q

TNF beta由什麼分泌 是幹嘛的?

A

由T cell分泌 可殺腫瘤和引起發燒

24
Q

干擾素由什麼樣的細胞釋出

A

由被病毒感染的細胞釋出

25
Q

Alpha干擾素由什麼產生

A

由白血球產生

26
Q

Beta干擾素由什麼產生

A

纖維母細胞產生

27
Q

Gamma干擾素由什麼產生

A

由Tcell產生

28
Q

B cell的攻擊目標是?

A

入侵物

29
Q

補體的攻擊目標是?

A

入侵物

30
Q

補體如何攻擊目標

A

形成細胞膜攻擊複合體

31
Q

抗微生物蛋白有哪兩個

A

drosomysin

defensin

32
Q

drosomysin是對抗什麼

A

真菌

33
Q

defenin是對抗什麼

A

細菌

34
Q

類毒素疫苗有哪兩種

A

白喉

破傷風

35
Q

死箘疫苗有哪五個例子

A
百日咳 
日本腦炎
傷寒 
霍亂
沙克疫苗
36
Q

減毒性活菌疫苗

A

卡介苗
麻疹
沙賓疫苗

37
Q

遺傳工程疫苗

A

B肝疫苗

利用酵母菌

38
Q

G+菌的細胞壁主要由什麼組成

A

肽聚糖

39
Q

G-菌和G+菌細胞壁主要的差異是什麼

A

G-菌有脂多糖

40
Q

B cell主要負責?

A

體液免疫反應

41
Q

T cell 主要負責

A

細胞免疫反應

42
Q

B cell對抗

A

細菌

43
Q

T cell對抗

A

病毒

破壞真菌 原生動物與寄生蟲

44
Q

效應細胞effector cell
為免疫反應中真正保衛個體的細胞
有哪三個

A

漿細胞
Tc cell
Th cell

45
Q

漿細胞如何產生?

A

B cell受刺激而活化 分裂成漿細胞

46
Q

MHC 1功能 兩個

A

Tc cell和MHC 1結合後發揮毒性細胞功能

與器官排斥有關

47
Q

MHC2功能

A

把處理過的抗原呈現給Th cell,Th cell只能辨識MHC2

48
Q

半衰期最長的抗體是?

A

IgG

49
Q

可通過胎盤的抗體是

A

IgG

50
Q

在初乳中的抗體是

A

IgA

51
Q

通常位在B cell細胞膜表面的抗體是

A

IgD

52
Q

寄生蟲感染會上升的抗體是

A

IgE

53
Q

即發形過敏反應參與的淋巴球是?

A

B cell

54
Q

遲發形過敏反應參與的淋巴球是

A

T cell

55
Q

即發性過敏反應常見的過敏症是

A

乾草熱 哮喘及大部分其他過敏反應

56
Q

遲發性過敏反應常見的過敏症是

A

接觸性皮膚炎

57
Q

HIV可以攻擊哪三個

A

CD4
CXCR4
CCR5