17 - 55 yo F with vaginal bleeding Flashcards

1
Q

menopause: definition

- what is thought to lead to the majority of postmenopausal symptoms?

A
  • ovaries are depleted of follicles and produce less estrogen
  • lack of estrogen
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2
Q
  • recommendations from the American society for colposcopy and cervical pathology call for pap smear screening to start at age ____ and continue every ____ years until age ____
  • preferred screening from age 30-65 is with ____ testing in addition to the __________ test every ____ years
A
  • 21
  • 3
  • 30
  • HPV
  • cytology (Pap)
  • 5

*cytology alone in the 30-65 group every 3 yeas is also considered acceptable

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3
Q

what is the single best predictor of low bone mineral density?

A

lower body weight (under 70 kg)

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4
Q

what is the relationship of obesity to osteoporosis?

A

NOT a risk factor NOR is it protective

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5
Q

most women over 50 should consume an average of _______ of calcium and _______ of vitamin D

A
  • 1200 mg

- 800-1000 IU

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6
Q

a T score of less than ____ indicates osteoporosis

A

-2.5

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7
Q

cervical polyps are most common in women of what age range?

A
  • postpartum

- perimenopausal

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8
Q

what are the modalities for evaluating postmenopausal bleeding?

A
  • transvaginal US
  • endometrial biopsy
  • CBC
  • FSH and LH
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9
Q

what are the capabilities / roles of transvaginal US in evaluating vaginal bleeding?

A
  • endometrial thickness
  • fibroids / leiomyomas
  • focal uterine masses
  • ovarian pathology
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10
Q

endometrial thickness should be less than _________

A

4 or 5 mm

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11
Q

what is the traditional gold standard for evaluating postmenopausal bleeding?

A

endometrial biopsy

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12
Q

what is the role of inhibin? how is it affected by menopause?

A
  • negative feedback of pituitary FSH secretion and synthesis
  • less inhibin is produced by ovarian granulosa cells; therefore, circulating FSH and LH levels increase (elevated FSH confirms menopause)
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13
Q

combined estrogen and progesterone use beyond ____ years increases the risk of __________

A
  • 3 years

- breast cancer

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14
Q

beginning hormone therapy after the age of 60 increases the risk for ________________

A

coronary artery disease

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15
Q

hormone therapy increases the risk of ________ at least for the first 1-2 years

A

stroke

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16
Q

what bisphosphonate can be given (IV) to patients who cannot tolerate oral bisphosphonates?

A

zoledronic acid

17
Q

raloxiphen is only indicated to prevent what type of fracture specifically?

A

vertebral

18
Q

calcitonin has been shown to prevent what type of fracture specifically?

A

vertebral

19
Q

what non-hormone therapy drugs can be used to treat symptoms of menopause?

A
  • antidepressants
  • clonidine
  • gabapentin