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16. Antiparasitos > 16.2.2 Inhibidores de la síntesis de ácido fólico: SULFADOXINA-PIRIMETAMINA > Flashcards

16.2.2 Inhibidores de la síntesis de ácido fólico: SULFADOXINA-PIRIMETAMINA Flashcards

1
Q

Qué enzima inhibe sulfadoxina?

A

Dihidropteroato sintetasa

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2
Q

Qué enzima inhibe pimetmaina?

A

DIHIDROFOLATO REDUCTASA

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3
Q

Capcidad que le brinda una semivida prolongada a sulfadoxina-primetamina

A

su unión alta a proteínas

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4
Q

Contraindicaciones de sulfadoxina-primetamina

A

hierdsensibilidad a sulfonamida e insuficiencia hepática o orenal

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5
Q

Reacciones adversad de sulfadoxina-primetamina

A

anemia megalobástica, hepatitis, nefrotoxicidad

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6
Q

Categoría en embarazo de sulfadoxina-primetamina

A

C

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7
Q

Efectos adveros del uso prolongado de sulfadoxina-primetamina

A

deterioro de la división celular (médula ósea y epitelio gastrointestinal)

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8
Q

Profilaxis para P.falciparum en personas que viajan

A

25mg una vez por semana

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16. Antiparasitos (13 decks)

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