1.6.2 Hydrolysis & Synthesis of ATP Flashcards
Energy released during the reactions of respiration is transferred to the molecule
adenosine triphosphate (ATP)
ATP is a small and soluble molecule that provides
a short-term store of chemical energy that cells can use to do work
The use of ATP as an ‘energy-currency’ is beneficial for many reasons, the hydrolysis of ATP can be carried out
quickly and easily wherever energy is required within the cell by the action of just one enzyme, ATPase
The use of ATP as an ‘energy-currency’ is beneficial for many reasons, a useful
quantity of energy is released from the hydrolysis of one ATP molecule - this is beneficial as it reduces waste but also gives the cell control over what processes occur
ATP is relatively stable at
cellular pH levels
Hydrolysis of ATP to adenosine diphosphate (ADP) and an inorganic phosphate group (Pi) is catalysed by the enzyme
ATP hydrolase sometimes called ‘ATPase’
The hydrolysis of ATP can be coupled to energy-requiring reactions within cells such as
- the active transport of ions up a concentration gradient
- enzyme controlled reactions that require energy
- muscle contraction and muscle fibre movement
As ADP forms free energy is released that can be used for processes within a cell eg
DNA synthesis
As ADP forms free energy is released that can be used for processes within a cell eg DNA synthesis:q
- removal of one phosphate group from ATP releases 30.8 kJ mol -1 of energy, forming ADP
- removal of a second phosphate group from ADP also releases 30.8 kJ mol-1 of energy, forming AMP
- removal of the third and final phosphate group from AMP releases 14.2 kJ mol-1 of energy, forming adenosine
The inorganic phosphate released during the hydrolysis of ATP can be used to
phosphorylate other compounds, often making them more reactive
Features of ATP Table
ATP is formed when
ADP is combined with an inorganic phosphate (Pi) group by the enzyme ATP synthase
ATP is formed when ADP is combined with an inorganic phosphate (Pi) group by the enzyme ATP synthase
- this is an energy-requiring reaction
- water is released as a waste product (therefore ATP synthesis is a condensation reaction)
ATP is made during the reactions of
respiration and photosynthesis
ATP can be made in two different way
- substrate-linked phosphorylation (occurs in the glycolysis stage of respiration)
- chemiosmosis (occurs in the electron transport chain stage of respiration)