1.6 Cell Cycle Regulation

Question 1

Cell Cycle Checkpoints

Answer 1

contains numerous checkpoints that ensure the fidelity and viability of continued cell division

Question 2

G1 checkpoint

Answer 2

monitors potential growth conditions, such as nutrients 

Question 3

G2 checkpoint

Answer 3

Monitor states of pre-mitotic cell (suitable size)

Identifies and repairs any DNA replication errors

Question 4

Cyclins

Answer 4

proteins that control progression of the cell cycle

bind to cycline dependent kinases

Question 5

Cancer

Answer 5

caused by uncontrolled cell division

Question 6

Metastasis

Answer 6

Spread of cancer from original cite to new location (secondary tumor)

Question 7

Causes of cancer

Answer 7

Mutagens

Genetics

Question 8

Mutagens

Answer 8

Cause the change of genetic material in cells

Question 9

Examples of mutagens

Answer 9

UV rays

Arsenic exposure

Viruses

Question 10

Genetics

Answer 10

Proto-oncogens stimulate cell growth

Tumor supressor genes repress cell cycle progression

Question 11

Tumor suppression gene

Answer 11

repress cell cycle progression

Question 12

Proto-oncogen mutations…

Answer 12

CAUSE CANCER CAUSING ONCOGENS

Question 13

Cell death occurs in 2 ways

Answer 13

Necrosis

Apoptosis

Question 14

Necrosis

Answer 14

Uncontrolled cell homicide

so loses functional control due to injury or toxins

Destabilization

cell bursts and releases its contents

Question 15

Apoptosis

Answer 15

Programmed cell suicide

controlled event triggered by mitochondrial proteins

Contents are packed in blebs and are released to be recycled