1.6 Flashcards
What do chromosomes consist of
DNA and histone
When are chromosomes visible
After they condense at the onset of cell division
Following DNA replication what does a chromosome exist as
Two identical sister chromatids joined by the centromere
What do chromosomes contain
Genes that code for specific polypeptides
How manu chromosomes do humans have
46
23 pairs
What are homologous chromosomes?
Chromosomes that are the same size and shape and carry the same genes but these may be different versions called alleles.
One chromosome of
each pair comes from each
parent
Two complete sets of chromosomes
Diploid 2n
Humans - 46
What is haploid and where are haploid numbers found
n
Human gametes
What are the stages of the cell cycle
Interphase
Mitosis
Cytokines
Define interphase
a period of synthesis and growth during the cell cycle
Describe interphase
- longest cell cycle phase
- very metabolically active
- DNA quantity doubles (chromosome number remains as it becomes 2 sister chromatids)
- protein synthesis
- organelle replication
What is mitosis
Chromosomes are arranged and separated prior to cell division
Results in two genetically identical cells that contain the same number or chromosomes as the parent cell
What happens during prophase of mitosis
• Chromosomes condense to become shorter and thicker
• Chromosomes become visible as two sister chromatids attached by a centromere
• Centrioles move to opposite
poles (not higher plants)
• Nuclear envelope disintegrates
• Nucleolus disappears
Which stage
Prophase of mitosis
What happens during metaphase of mitosis
- Spindle forms
* Chromosomes align at the equator of the cell attached to spindle microtubules via centromere
Which stage
Metaphase of mitosis
What happens during anaphase of mitosis
- Spindle fires shorten
* Centromeres divide, and chromatids are pulled towards opposite poles
Which stage
Anaphase of mitosis
What happens during telophase of mitosis
• Chromatids reach poles and become indistinct by uncoiling • Nuclear envelope reforms • Nucleolus reforms • Spindle disintegrates
Which stage
Telophase of mitosis
What is cytokinesis
the division of the cytoplasm to form
two daughter cells
Animal cytokinesis
membrane infolds via cleavage furrow until the two cells become separated