15) Control & Co-ordination Flashcards
list 5 key ideas about hormones
- proteins or steroids
- released by endocrine glands
- directly into the blood
- act as messengers
- affect target organs/ cells
what are 3 peptide hormones
- ADH
- insulin
- glucagon
(cell signalling molecules)
how do peptide hormones pass through the membrane?
- cannot pass through directly
- since they are hydrophilic
- so they bind to receptors in the plasma membrane of a target cell
5 differences between the endocrine system and the nervous system
Endocrine system
- communication = HORMONE
- nature of communication= chemical
- mode of transmission = blood
- response destination = target organs/cells
- transmission & response speed = slower
- effects = widespread
- duration = longlasting/permanent
Nervous system
- communication = action potential/impulse
- nature of communication= electrical (& chemical)
- mode of transmission = neurone
- response destination = muscle/gland
- transmission & response speed = faster
- effects = specific
- duration = short lived/temporary
describe the structure of a motor neurone
- cell body at end of neurone
- cell body in CNS
- long axon
- dendrites attached to cell body
describe the structure of a sensory neurone
- cell body in middle of neurone
- nucleus in cell body
- short axon
- dendrites attached to dendron
- long dendron
- many mitochondria in cell body
- many RER/ribosomes in cell body
- synaptic knobs
- myelin sheath/ schwann cells
- nodes of Ranvier
how does the myelin sheath increase the speed of conduction of nerve impulses
- it insulates axon
- action potential only at nodes of Ranvier
- local circuits set up between nodes
- action potential jumps from node to node
- saltatory conduction
what is a transducer
convert energy in one form (light/heat) into electrical energy within a sensory neurone
role of chomoreceptor cell in detecting stimuli and stimulating action potential
- chemicals act as a stimulus
- specificity of chomoreceptors
- Na+ diffuse into cell via microvilli
- membrane depolarised
- receptor potential
- stimulates opening of Ca+ channels
- Ca+ enter the cell
- vesicles with neurotransmitter move/fuse
- neurotransmitter released by exocytosis
- neurotransmitter stimulates action potential
How is a resting potential set up and maintained in a myelinated neurone [9]
- Na+ moves out of the cell and K+ moves into the cell. by active transport.
- 3 Na+ for every 2 K+.
- sodium potassium pump.
- against concentration gradient
- K+ diffuses out of cell & Na+ diffuses into.
- by facilitated diffusion.
- membrane more permeable to K+ so more K+ goes out than Na+ in.
- inside of the cell is more negative than the outside
- membrane polarised
- resting potential = -70mV
describe the transmission of an action potential in a myelinated neurone [9]
- stimulus occurs
- Na+ channels open
- Na+ enters the cell
- causes depolarisation as inside of the cell becomes less negative
- Na+ channels close
- K+ channels open
- K+ moves out of the cell
- repolarisation = inside becomes negative
- local circuits
- myelin sheath insulate axon
- action potential ONLY at nodes of Ranvier
- saltatory conduction (action potential jumps from node to node)
- hyperpolarisation
- back to resting potential
what is the importance of the refractory period
- ensures action potentials are discrete events, stopping them from merging into one another
- ensures the charge of the membrane potential is generated ahead rather than behind the original action depolarisation
- so impulse can only travel in one direction
what is a synapse
where two neurones meet but do not actually touch - a tiny gap
synaptic transmission
- Ca2+ channels open
- Ca2+ enters presynaptic knob
-vesicles contain neurotransmitter ACh - vesicles fuse with presynaptic membrane
- ACh released by exocytosis
- ACh diffuses across the cleft
- binds to receptors on post-synaptic membrane
- Na+ channels open
- Na+ enters post-synaptic neurone
what is the role of acetylcholinesterase [2]
- breaks down neurotransmitter ACh
- recycles ACh
why are there tight junctions between chemoreceptor cells
so theres no movement of substances between the chemoreceptor cells
breakdown the structure of a muscle
- muscle
- muscle fibres
- myofibrils
- myofilaments
2 types of myofilaments
actin - thin
myosin - thick
what are myofilaments
repeating contracting units in a sarcomere