15 AMNIOTIC FLUID Flashcards
Which of the following is not a function of amniotic fluid?
A. Allows movement of the fetus
B. Allows exchange of carbon dioxide and oxygen
C. Protects the fetus from extreme temperature changes
D. Acts as a protective cushion for the fetus
B. Allows exchange of carbon dioxide and oxygen
What is the primary cause of the normal increase in amniotic fluid as a pregnancy progresses?
A. Fetal cell metabolism
B. Fetal swallowing
C. Fetal urine
D. Transfer of water across the placenta
C. Fetal urine
Which of the following is not a reason for decreased amounts of amniotic fluid?
A. Fetal failure to begin swallowing
B. Increased fetal swallowing
C. Membrane leakage
D. Urinary tract defects
A. Fetal failure to begin swallowing
Why might a creatinine level be requested on an amniotic fluid?
A. Detect oligohydramnios
B. Detect polyhydramnios
C. Differentiate amniotic fluid from maternal urine
D. Evaluate lung maturity
C. Differentiate amniotic fluid from maternal urine
Amniotic fluid specimens are placed in amber-colored tubes before sending them to the laboratory to prevent the destruction of:
A. Alpha-fetoprotein
B. Bilirubin
C. Cells for cytogenetics
D. Lecithin
B. Bilirubin
How are specimens for FLM testing delivered to and stored in the laboratory?
A. Delivered on ice and refrigerated
B. Immediately centrifuged
C. Kept at room temperature
D. Delivered in a vacuum tube
A. Delivered on ice and refrigerated
Why are amniotic specimens for cytogenetic analysis
incubated at 37°C before analysis?
A. To detect the presence of meconium
B. To differentiate amniotic fluid from urine
C. To prevent photo-oxidation of bilirubin to biliverdin
D. To prolong fetal cell viability and integrity
D. To prolong fetal cell viability and integrity
Match the following colors in amniotic fluid with their significance.
COLORLESS
A. Fetal death
B. Normal
C. Presence of bilirubin
D. Presence of meconium
B. Normal
Match the following colors in amniotic fluid with their significance.
DARK GREEN
A. Fetal death
B. Normal
C. Presence of bilirubin
D. Presence of meconium
D. Presence of meconium
Match the following colors in amniotic fluid with their significance.
RED-BROWN
A. Fetal death
B. Normal
C. Presence of bilirubin
D. Presence of meconium
A. Fetal death
Match the following colors in amniotic fluid with their significance.
YELLOW
A. Fetal death
B. Normal
C. Presence of bilirubin
D. Presence of meconium
C. Presence of bilirubin
A significant rise in the OD of amniotic fluid at 450 nm indicates the presence of which analyte?
A. Bilirubin
B. Lecithin
C. Oxyhemoglobin
D. Sphingomyelin
A. Bilirubin
Plotting the amniotic fluid OD on a Liley graph represents the severity of hemolytic disease of the fetus and newborn.
A value that is plotted in zone II indicates what condition of the fetus?
A. No hemolysis
B. Mildly affected fetus
C. Moderately affected fetus that requires close monitoring
D. Severely affected fetus that requires intervention
C. Moderately affected fetus that requires close monitoring
The presence of a fetal neural tube disorder may be detected by:
A. Increased amniotic fluid bilirubin
B. Increased maternal serum alpha-fetoprotein
C. Decreased amniotic fluid phosphatidyl glycerol
D. Decreased maternal serum acetylcholinesterase
B. Increased maternal serum alpha-fetoprotein
True or False: An AFP MoM value greater than two times the median value is considered an indication of a neural
tube disorder.
True
When severe HDFN is present, which of the following tests on the amniotic fluid would the physician not order
to determine whether the fetal lungs are mature enough
to withstand a premature delivery?
A. AFP levels
B. Foam stability index
C. Lecithin/sphingomyelin ratio
D. Phosphatidyl glycerol detection
A. AFP levels
True or False: Before 35 weeks’ gestation, the normal L/S ratio is less than 1.6.
True
When performing an L/S ratio by thin-layer
chromatography, a mature fetal lung will show:
A. Sphingomyelin twice as concentrated as lecithin
B. No sphingomyelin
C. Lecithin twice as concentrated as sphingomyelin
D. Equal concentrations of lecithin and sphingomyelin
C. Lecithin twice as concentrated as sphingomyelin
True or False: Phosphatidyl glycerol is present with an
L/S ratio of 1.1.
True
A rapid immunologic test for FLM that does not require
performance of thin-layer chromatography is:
A. AFP levels
B. Amniotic acetylcholinesterase
C. Amniostat-FLM
D. Bilirubin scan
C. Amniostat-FLM
Does the failure to produce bubbles in the Foam Stability Index indicate increased or decreased lecithin?
A. Increased
B. Decreased
B. Decreased
The presence of phosphatidyl glycerol in amniotic fluid fetal lung maturity tests must be confirmed when:
A. Hemolytic disease of the fetus and newborn is present
B. The mother has maternal diabetes
C. Amniotic fluid is contaminated by hemoglobin
D. A neural tube disorder is suspected
B. The mother has maternal diabetes
A lamellar body count of 50,000 correlates with:
A. Absent phosphatidyl glycerol and L/S ratio of 1.0
B. L/S ratio of 1.5 and absent phosphatidyl glycerol
C. OD at 650 nm of 1.010 and an L/S ratio of 1.1
D. OD at 650 nm of 0.150 and an L/S ratio of 2.0
D. OD at 650 nm of 0.150 and an L/S ratio of 2.0