14.3 Flashcards
Mendelian view of heredity and variation
An organism;s phenotype reflects its genotype and unique environmental history
Mendelian genetics endures as the foundation of what?
Human genetics
Pedigree
Family tree that describes the interrelationships of parents and children across generations
What can be used to make predications about future offspring?
Pedigrees
Many genetic disorders are inherited how?
Recessive matter
Carriers
Heterozygous individuals who carry the recessive disorders are born to carry parents
What is an example of a recessive condition?
Albinism
A recessive allele that causes a disease is rare and the chance of two carriers meeting and mating is…?
Low
Consanguineous matings
Increase the chance of mating between two carriers of the same rare allele; matings between close relatives
Cystic fibrosis
Most common lethal genetic disease in the US, striking 1/2500 people in European descendants
What genetic disease includes symptoms denoting mucus buildup in some internal organs and abnormal absorption of nutrients in the small intestine
Cystic fibrosis
Sickle-cell disease frequency
Affects one out of 400 African-Americans
What is sickle-cell disease
A disease that is caused by the substitution of a single amino acid in the hemoglobin protein in red blood cells
Heterozygotes or homozygotes have the sick-cell trait are usually healthy but may have some symptoms?
Heterozygotes
Rare
Dominant alleles that cause a lethal disease and arise by mutation
