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4001 > 14 Anti-depressants > Flashcards

14 Anti-depressants Flashcards

1
Q

Causes of depression?

A
  • low levels of serotonin

- reduction in serotonin receptors in hippocampus

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2
Q

Mechanism of action of Mono Amine Oxidase Inhibitors (MAOI)?

A
  • inhibit activity of MAO enzymes
  • MAO breaks down norepinephrine/ serotonin and dopamine
  • Inhibiting MAO increases level of all 3 transmitters
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3
Q

Examples of Mono Amine Oxadase Inhibitors (MAOI)?

A
  • Phenelzine
  • Selgiline
  • Tranylcypromine
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4
Q

Side effects of Mono Amine Oxadase Inhibitors (MAOI)?

A
  • Weakness
  • Dizziness
  • Headache
  • Fatigue
  • Weight gain
  • Impotence
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5
Q

What should not be used in combination with Mono Amine Oxadase Inhibitors (MAOI)?

A
  • SSRI
  • Tricyclic
  • Morphine
  • Tramadol
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