13: Neurology Flashcards
CNS
- Central Nervous System
- Consists of the spinal cord and the brain
PNS
- Peripheral Nervous System
- Nerves connecting to the CNS that are sensory neurons & motor neurones connecting to effectors
Somatic Nervous System
-Conscious movements/actions that is voluntary
Automatic Nervous System
- Involuntary unconscious actions (heart beat, myotatic reflex)
- subconscious
What is the automatic nervous systems sub sections?
- Sympathetic
- Parasympathetic
Sympathetic motor system
- Involves noradrenaline being released
- This leads to an increase in the activity of the effectors
Parasympathetic motor system
- Involves the neurotransmitter ACh ( Acetylcholine )
- This leads to relaxing of the effectors
Structures in the Human Brain
- Skull
- Dura
- Cerebrum
- Cerebellum
- Corpus Callosum
- Medulla oblongata
- Hypothalamus
- Pituitary Gland
How is a resting potential maintained?
-Na+ and K+ ion pumps maintain the resting potential
Structural similarities between sensory and motor neurones.
- Soma (cell body)
- Axon(s)
- Dendrites
- Voltage gated K+ and Na+ ion channels
- myelin sheath
- Schwann Cells (glial cells)
Why is the Pacinian corpuscle described as a transducer?
-Converts mechanical energy into electrical energy (action potentials)
How is the strength and intensity of a stimulus relayed to the brain?
- The frequency of action potentials propagated
- The higher the frequency the stronger the stimulus
The roles of synapses
- Allows for cell signalling
- Unidirectional
- Filter low level stimuli
- enables memories
- Prevents over stimulation
- Allows for low level stimuli to be amplified
- Allows for the convergence/divergence of impulses
Explain the difference between the speed of conduction of an action potential in a myelinated and non-myelinated neurone
- Conduction is faster in the myelinated part of the neurone (larger membrane resistance smaller axial resistance)
- Action potential can only be generated at the nodes of Ranvier in myelinated
- Longer Local circuits
- Ion movement can only happen at the nodes
- Saltatory conduction (jumping from node to node)
How can a toxin interfere with the release of neurotransmitters?
- interfere with the binding of the vesicle to the pre-synaptic membrane
- interfere with the movement of Ca+ ions
- interfere with the reuptake of the neurotransmitters
- interfere with the formation of endosomes (vesicles)