1.3 Anatomy Hypothalamus & Pituitary Flashcards
Where is the hypothalamus located?
ventral diencephalon
What are the borders of the hypothalamus?
Ant: optic chiasm Lat: optic tracts Post: mamillary bodies Medial: 3rd ventricle Sup: hypothalamic sulcus
What are the 2 important nuclei associated with the hypothalamus?
Paraventricular nucleus
Supraoptic nucleus
AKA of post pituitary
neurohypophysis
AKA of ant. pituitary
adenohypophysis
boney landmarks surrounding pituitary?
ant: tuberculum sellae
Post: dorsum sellae
inf: hypophyseal fossa
post and ant clinoid process
what is the hypothalamus derived from
prosencephalon
what layer is the pituitary derived from?
ectoderm
what are the 3 cell types of adenohypophosis?
acidophils
basophils
chromophobes
general histology of p ituitary
parnchyma consists of cords of small irregular groups of cells
What stain do you use to see the 3 cell types?
H and E stain based on affinity of cytoplasmic granules
Acidophils: staining, cell type
stains bright pink
somatotropes- GH
Mammotropes- PRL
Basophils: staining, cell type?
stains purple
Thyrotropes-TSH
Corticotropes- ACTH
Gonadotropes- FSH, LH
Chromophobes: staining, cell types
appear translucent
EM shows they are old basophils and acidophils
What ectoderm makes up the adenohypophysis
oral ectoderm from rathke’s pouch