(1.2) Management of Asthma Flashcards

1
Q

Albuterol class and indication

A

SABA

asthma
acute bronchitis
bronchiolitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

terbutaline class and indication

A

SABA ONLY ONE AVAILABLE AS SUBQ but is a sulfur drug

> 12 yrs old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

albuterol adverse effects/warning

A

headache/dizziness/insominia/dry mouth/cough

paradoxical bronchospasm/asthma deterioration/CV effects/anaphylaxis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

terbutaline adverse effects/warning

A

is a sulfur drug

do not use for tocolysis

headache/nausea/tachycardia/palipitations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

metaproterenol class and indication

A

SABA

bronchodilator for bronchial asthma and reversible bronchospasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

metaproterenol adverse effects/warning

A

significant CV effect

paradoxical bronchospasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

pirbuterol class and indication

A

SABA

> 12 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

pirbuterol adverse effects/warning

A

CV that can be significant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

SABAs are used

A

B2 agonist

functional antagonist to reverse bronchospasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

levalbuterol class and indication

A

SABA

> 4 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

levalbuterol adverse effects/warning

A

life threatening paradoxical bronchospasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Fomoterol class and indication

A

LABA

> 5 years old

add on to corticosteroid
maintenance of bronchoconstriction in COPD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

fomoterol adverse effects/warning

A

needs concomitant use of other long term control

LABAs increase risk of asthma related death/hospitalization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Salmeterol class and indication

A

LABA

> 4 years old

Exercise induced bronchospasm
maintenance as well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

idacaterol and vilanterol class and indication

A

LABA

COPD/chronic bronchitis/emphysema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

olodaterol class and indication

A

LABA

long term once daily

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

LABA basic info

A

LABA should be used in concomitant use of a long-term asthma control medication such as an inhaled corticosteroid.

LABA increase the risk of asthma-related deaths and asthma-related hospitalizations

Prescribe for asthma only as concomitant therapy with a long-term control medication such as an inhaled corticosteroid.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Formoterol is combined with

A

mometasone
or
budesonide

19
Q

salmeterol is combined with

A

fluticasone

20
Q

anticholinergic drugs warnings

A

pts with CAD dose restriction to 2-3mg to avoid systemic effects such as tachycardia

21
Q

ipratropium class and indication

A

anticholinergic

maintenance treatment for bronchospasm

aerosol so avoids systemic effects

22
Q

tioropium class and indication

A

anticholinergic

long term once daily maintenance of bronchospasm

COPD

23
Q

aclidinium class and indication

A

anticholinergic

long term maintenance of bronchospasm

COPD

24
Q

where is theobromine found

25
methylxanthines
theophylline theobromine caffeine
26
methylxanthine usage
smooth muscle relaxation suppression of response of airway to stimuli most widely used
27
most effective controllers for asthma
ICS
28
ICS are given
twice daily first line of step then LABA are given afterwards
29
beclomethasone class and indication
ICS >5 years old
30
ICS general adverse effects/warning
be careful when coming off systemic corticosteroids because death due to adrenal insufficiency have happened in asthmatic patients number of months are required to recover HPA axis from systemic corticosteroids
31
budesonide class and indication
ICS >6 years old
32
budesonide adverse effects/warning
do not use for primary treatment of status asthmaticus and acute episodes of asthma
33
ciclesonide class and indication
ICS >12 years old
34
ciclesonide adverse effects/warning
avoid if candida albicans of mouth/pharynx TB/bacterial/viral/parasitic infection
35
Flunisolide class and indication
ICS >6 years old indicated for pts requiring oral corticosteroid therapy and may reduce the need of them
36
fluticasone class and indication
ICS >4 years old
37
fluticasone adverse effects/warning
candida albicans may occur with this drug and monitor for it make sure rinse mouth out to prevent candida albicans infection
38
mometasone
ICS >4 yrs old avoid if pt has known hypersensitivity to milk
39
triamclinolone
ICS indicated if systemic corticosteroids are needed be cautious if patient is on corticosteroids
40
Montelukast
Leukotriene antagonist CysLT1 receptor inhibiting LTD4 and CysLT1 without any agonist activity is primarily for allergies and not for acute bronchospasm
41
leukotriene antagonists
treatment and prevention of acute asthmatic attacks bind CysLT blocking activation and inflammatory cascade
42
zafirlukast
selective antagonist for D4/E4 leukotriene receptors >5 years old hepatotoxic
43
zileuton
was a drug withdrawn in 2008 LTB4/LTC4/LTD4/LTE4 >12 years old very hepatotoxic
44
omalizumab
anti-IgE Ab >6 years old also for chronic idiopathic urticaria in >12 yrs old who don't fully respond to H1 antihistamine do not use for anaphylaxis unless in a hospital