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CPR II Exam II > (1.2) Management of Asthma > Flashcards

(1.2) Management of Asthma Flashcards

1
Q

Albuterol class and indication

A

SABA

asthma
acute bronchitis
bronchiolitis

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2
Q

terbutaline class and indication

A

SABA ONLY ONE AVAILABLE AS SUBQ but is a sulfur drug

> 12 yrs old

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3
Q

albuterol adverse effects/warning

A

headache/dizziness/insominia/dry mouth/cough

paradoxical bronchospasm/asthma deterioration/CV effects/anaphylaxis

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4
Q

terbutaline adverse effects/warning

A

is a sulfur drug

do not use for tocolysis

headache/nausea/tachycardia/palipitations

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5
Q

metaproterenol class and indication

A

SABA

bronchodilator for bronchial asthma and reversible bronchospasm

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6
Q

metaproterenol adverse effects/warning

A

significant CV effect

paradoxical bronchospasm

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7
Q

pirbuterol class and indication

A

SABA

> 12 years old

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8
Q

pirbuterol adverse effects/warning

A

CV that can be significant

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9
Q

SABAs are used

A

B2 agonist

functional antagonist to reverse bronchospasm

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10
Q

levalbuterol class and indication

A

SABA

> 4 years old

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11
Q

levalbuterol adverse effects/warning

A

life threatening paradoxical bronchospasm

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12
Q

Fomoterol class and indication

A

LABA

> 5 years old

add on to corticosteroid
maintenance of bronchoconstriction in COPD

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13
Q

fomoterol adverse effects/warning

A

needs concomitant use of other long term control

LABAs increase risk of asthma related death/hospitalization

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14
Q

Salmeterol class and indication

A

LABA

> 4 years old

Exercise induced bronchospasm
maintenance as well

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15
Q

idacaterol and vilanterol class and indication

A

LABA

COPD/chronic bronchitis/emphysema

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16
Q

olodaterol class and indication

A

LABA

long term once daily

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17
Q

LABA basic info

A

LABA should be used in concomitant use of a long-term asthma control medication such as an inhaled corticosteroid.

LABA increase the risk of asthma-related deaths and asthma-related hospitalizations

Prescribe for asthma only as concomitant therapy with a long-term control medication such as an inhaled corticosteroid.

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18
Q

Formoterol is combined with

A

mometasone
or
budesonide

19
Q

salmeterol is combined with

A

fluticasone

20
Q

anticholinergic drugs warnings

A

pts with CAD dose restriction to 2-3mg to avoid systemic effects such as tachycardia

21
Q

ipratropium class and indication

A

anticholinergic

maintenance treatment for bronchospasm

aerosol so avoids systemic effects

22
Q

tioropium class and indication

A

anticholinergic

long term once daily maintenance of bronchospasm

COPD

23
Q

aclidinium class and indication

A

anticholinergic

long term maintenance of bronchospasm

COPD

24
Q

where is theobromine found

A

chocolate

25
Q

methylxanthines

A

theophylline
theobromine
caffeine

26
Q

methylxanthine usage

A

smooth muscle relaxation
suppression of response of airway to stimuli

most widely used

27
Q

most effective controllers for asthma

A

ICS

28
Q

ICS are given

A

twice daily

first line of step then LABA are given afterwards

29
Q

beclomethasone class and indication

A

ICS

> 5 years old

30
Q

ICS general adverse effects/warning

A

be careful when coming off systemic corticosteroids because death due to adrenal insufficiency have happened in asthmatic patients

number of months are required to recover HPA axis from systemic corticosteroids

31
Q

budesonide class and indication

A

ICS

> 6 years old

32
Q

budesonide adverse effects/warning

A

do not use for primary treatment of status asthmaticus and acute episodes of asthma

33
Q

ciclesonide class and indication

A

ICS

> 12 years old

34
Q

ciclesonide adverse effects/warning

A

avoid if candida albicans of mouth/pharynx

TB/bacterial/viral/parasitic infection

35
Q

Flunisolide class and indication

A

ICS

> 6 years old

indicated for pts requiring oral corticosteroid therapy and may reduce the need of them

36
Q

fluticasone class and indication

A

ICS

> 4 years old

37
Q

fluticasone adverse effects/warning

A

candida albicans may occur with this drug and monitor for it

make sure rinse mouth out to prevent candida albicans infection

38
Q

mometasone

A

ICS

> 4 yrs old

avoid if pt has known hypersensitivity to milk

39
Q

triamclinolone

A

ICS

indicated if systemic corticosteroids are needed

be cautious if patient is on corticosteroids

40
Q

Montelukast

A

Leukotriene antagonist

CysLT1 receptor inhibiting LTD4 and CysLT1 without any agonist activity

is primarily for allergies and not for acute bronchospasm

41
Q

leukotriene antagonists

A

treatment and prevention of acute asthmatic attacks

bind CysLT blocking activation and inflammatory cascade

42
Q

zafirlukast

A

selective antagonist for D4/E4 leukotriene receptors

> 5 years old

hepatotoxic

43
Q

zileuton

A

was a drug withdrawn in 2008

LTB4/LTC4/LTD4/LTE4

> 12 years old

very hepatotoxic

44
Q

omalizumab

A

anti-IgE Ab

> 6 years old

also for chronic idiopathic urticaria in >12 yrs old who don’t fully respond to H1 antihistamine

do not use for anaphylaxis unless in a hospital

CPR II Exam II (21 decks)

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