1.2 Anaphylaxis

Question 1

Signs and Symptoms

Answer 1

1 CVS
compromise collapse
hypotension
tachycardia
bradycardia
arrhythmia 
arrest

2 Resp
Difficulty ventilate
high PAP
Bronchospasm
desat

3
Flushing
rash
urticaria

4
Facial swelling
angioedema

Question 2

Management - immediate

Answer 2

Protocol / kit

1
Call 4 help
Stop administration

2
secure airway ett
ventilate 100% FiO2

3
Supine
legs elevated
Wide bore IV access

4
Arrest - CPR ACLS

5
Admin 50mcg (0.5ml 1:10000) IV over 1 min
in collapse consider infusion

6
Additional support consider other IV Vasopressor
metaraminol / vasopressin

7
IV crystalloid rapid

8
Stable to ICU

Question 3

Mx Late

Answer 3

Corticosteroids

Antihistamine

Bronchodilator - if bronchospasm

Tryptases

Record keeping, critical incident and documentation

debriefing and councelling

letter to GP / Medi alert bracelet

Report to drug database

Notify anaphylaxis databse

Question 4

Allergy testing

Answer 4

Skin prick testing - IgE antibodies

Intradermal - if negskin prick

Serum IgE abod assay - sux

Radio allergosorbent test (rast)

Basophil stim test - flow cytometry