1.12 Gluconeogenesis Flashcards
1
Q
What amino acid must be made before PEP Carboxylase turns it into PEP?
A
OAA
2
Q
Where can OAA come from?
A
The TCA cycle or Pyruvate
3
Q
Where does pyruvate come from during GNG?
A
Lactate (via LDH), Alanine, and other Amino Acids
4
Q
How many ATP and NADH are needed for GNG?
A
6 ATP and 2 NADH
5
Q
What two molecules form F-1,6,bisP?
A
DHAP and Glyceraldehyde-3-P
6
Q
Where can DHAP come from?
A
Can be readily interconverted from Glyceraldehyde-3-P (reversible) and it can be formed from Glycerol-3-P (which comes from glycerol)
7
Q
What coenzyme is needed to turn pyruvate into OAA?
A
Biotin (along with pyruvate carboxylase enzyme)
