1103 EXAM Flashcards

1
Q

define anthropometry

A

study of human body measurements, including height, weight, and body circumferences, often used to assess body composition and health status

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

explain the concept of body composition

A

Body composition refers to the percentages of fat, bone, water, and muscle in the human body. It’s essential for assessing health and physical fitness.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Define Validity, Reliability, Precision and Accuracy

A

Validity: How well a test measures what it intends to measure.
Reliability: Consistency of test results across trials.
Precision: Reproducibility of measurements.
Accuracy: Closeness of measurements to the true value.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe how energy balance is regulated in the body

A

The body regulates energy balance through metabolic rate, hormonal controls (like insulin and glucagon), appetite control, and physical activity levels.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe basic concepts of molecule movement within biological systems.

A

Molecules move through diffusion, osmosis, and active transport to maintain cellular function and balance within biological systems.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Outline different cell transport mechanisms.

A

Passive Transport: Diffusion, facilitated diffusion, osmosis.
Active Transport: Requires energy (ATP), moves molecules against gradients.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What role do cell junctions play, and what are two types?

A

Cell junctions connect cells, providing support and communication.
Tight Junctions: Seal cells to prevent leakage.
Gap Junctions: Allow communication between cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Define an organ and an organ system.

A

An organ is a group of tissues working together for specific functions. An organ system is a group of organs that work together to perform complex body functions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Identify basic brain regions.

A

Includes cerebrum, thalamus/ hypothalamus, cerebellum, brainstem, and limbic system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Brain Cell types and their function

A

Neuron- rapid signal transmission

Astrocytes- maintain ‘blood- brain barrier’

Oligodendrocytes- provide myelin sheath

Microglia- Surveying, phagocytosis, removal of unused pathways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How can neurons exert different effects on body parts?

A

By varying neurotransmitters and receptor types, neurons influence responses in different body parts.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe the basic components of a sensory system.

A

Sensory systems include receptors (detect stimuli), neural pathways (carry information), and brain regions that process sensory information.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What receptors are required for each sensation

A

Vision: Photoreceptors (rods, cones).
Hearing: Mechanoreceptors (hair cells).
Taste: Gustatory receptors.
Smell: Olfactory receptors.
Touch: Mechanoreceptors, thermoreceptors, nociceptors.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Explain the physiological processes that allow us to taste.

A

Taste buds on the tongue detect chemicals in food, transduce signals into neural impulses sent to the brain, identifying five primary tastes: sweet, salty, sour, bitter, umami.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Describe the organization of the human gustatory system.

A

Taste receptors are located on taste buds primarily on the tongue and palate, and taste signals are processed in the gustatory cortex.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

How are the five primary tastes transduced?

A

Sweet: G- protein coupled receptors causing signaling cascade resulting in closure of leaky k+ channels –> therefore depolarization of cell and release of neurotransmitters

Umami: Glutamate receptors are G protein-coupled receptors which cause signaling cascade

Bitter: acts on G-protein-coupled receptors leading to signaling cascade resulting in opening of calcium channels

Salty: Sodium ions entering ion channels.

Sour: Proton (H+) ion channels closure of leaky k+ channels –> resulting
in depolarization of the
cell and release of
neurotransmitters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Explain physiological processes that allow us to smell.

A

Odor molecules bind to olfactory receptors in the nasal cavity, which activate neural signals processed in the olfactory bulb and then the olfactory cortex.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the differences between compact and spongy bone?

A

Compact Bone: Dense, provides strength and structure, yellow bone marrow
Spongy Bone: Porous, houses red bone marrow, supports lightweight structure.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Describe the components of a synovial joint.

A

Synovial joints have an articular cartilage, joint capsule, synovial membrane, synovial fluid, and supporting ligaments.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Describe the basic anatomy of muscle cells.

A

Muscle cells, or fibers, are long and cylindrical, containing myofibrils made up of actin and myosin filaments that enable contraction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Describe the steps in cross-bridge cycling.

A

CPDR

Cross-Bridge Formation: Myosin heads bind to actin.
Power Stroke: Myosin head pivots, pulling actin filament.
Detachment: ATP binds to myosin, releasing it from actin.
Reactivation: ATP hydrolysis repositions myosin head.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Identify differences between skeletal, cardiac, and smooth muscle

A

Skeletal Muscle: Voluntary, striated.
Cardiac Muscle: Involuntary, striated, found in heart.
Smooth Muscle: Involuntary, non-striated, found in organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

List the types of white blood cells and their roles.

A

Never Let Monkeys Eat Bananas

Neutrophils: Phagocytise bacteria.
Lymphocytes: B and T cells; immune response.
Monocytes: Become macrophages.
Eosinophils: Attack parasites.
Basophils: Release histamine in allergies.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Describe components of innate and adaptive immune systems.

A

Innate Immunity: First-line defenses (skin, mucous membranes), phagocytes.
Adaptive Immunity: Specific response, involving B and T cells, antibodies.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What are the main lymphoid organs and their functions?

A

Thymus: Matures T cells.
Bone Marrow: Produces blood cells.
Spleen: Filters blood, immune response.
Lymph Nodes: Filter lymph, house immune cells.

25
Q

Major differences between venous and arterial circulation?

A

Arterial: Carries oxygenated blood from heart, high pressure.
Venous: Carries deoxygenated blood to heart, low pressure, has valves.

26
Q

Identify ECG phases and relate to cardiac contraction.

A

P Wave: Atrial depolarization.
- SA node depolarises the current spreads through atria
- Atria contracts to eject blood into ventricles

QRS Complex: Ventricular depolarization.
- Current spreads down septum of the heart before spreading back up and around the ventricles
- Causes ventricles to contract and eject blood out into circulation

T Wave: Ventricular repolarization.
- As ventricles relax, muscle cells begin to repolarise

27
Q

What are the effects of insulin and glucagon?

A

Insulin: Lowers blood glucose, promotes glycogen storage.
Glucagon: Raises blood glucose by glycogen breakdown.

28
Q

What are the primary functions of the liver?

A

Metabolism, detoxification, protein synthesis, nutrient storage.

29
Q

Describe the four fundamental layers of the digestive tract.

A

Mucosa: Absorption and secretion.
Submucosa: Connective tissue with blood vessels.
Muscularis Externa: Smooth muscle for movement.
Serosa: Protective outer layer.

30
Q

What are methods to measure energy expenditure?

A

Direct calorimetry, indirect calorimetry, doubly labeled water method

31
Q

Define homeostasis and give an example

A

The maintenance of stable internal conditions;
- body temperature
- Body fluid

32
Q

Define major components of the respiratory system.

A

nose, pharynx, larynx, trachea, bronchi, lungs, and alveoli.

33
Q

Describe kidney processes of filtration, reabsorption, and secretion

A

Filtration: Blood plasma filtered at glomerulus.
Reabsorption: Essential nutrients reclaimed in tubules.
Secretion: Waste and excess ions added to filtrate.

34
Q

Compare the endocrine and nervous systems.

A

Endocrine: Slow, hormonal signaling, long-lasting effects.
Nervous: Fast, electrochemical signaling, short-term effects.

35
Q

Trace the path of sperm from production to fertilization

A

Produced in testes → stored in epididymis → moves through vas deferens → exits via urethra → reaches oocyte during fertilization.

36
Q

What are the four primary tissue types, their structures, and main functions?

A

Epithelial Tissue

Structure: Tightly packed cells with little extracellular matrix; forms continuous sheets.
Main Functions: Covers body surfaces, lines organs and cavities; protection, absorption, secretion, and filtration.
Connective Tissue

Structure: Diverse cells within an abundant extracellular matrix (e.g., fibers, ground substance).
Main Functions: Supports, binds, and protects organs; stores energy (fat), provides immunity (blood).
Muscle Tissue

Structure: Long, cylindrical or spindle-shaped cells; highly vascularized.
Main Functions: Responsible for movement; contracts to create force and cause movement, maintains posture, and generates heat.
Nervous Tissue

Structure: Made up of neurons (nerve cells) and supporting glial cells.
Main Functions: Transmits electrical signals for communication; detects stimuli, processes information, and directs responses.

37
Q

What are the types of bone cells and their primary functions?

A

Osteoblasts: Cells that build new bone by producing bone matrix and promoting mineralization.

Osteoclasts: Cells that break down bone tissue by resorbing bone matrix, releasing calcium into the bloodstream.

Osteocytes: Mature bone cells that maintain bone tissue and communicate with other bone cells for nutrient exchange and waste removal.

Osteogenic Cells: Bone stem cells that differentiate into osteoblasts for bone growth and repair.

38
Q

What is a negative feedback mechanism, and can you provide an example?

A

Concept: Negative feedback is a regulatory mechanism in which a change in a variable triggers a response that counteracts the initial fluctuation, helping maintain homeostasis.

Example: Blood glucose regulation. When blood glucose levels rise, the pancreas releases insulin, promoting glucose uptake by cells, which lowers blood glucose levels. As levels fall, insulin release decreases, maintaining stable glucose levels.

39
Q

What is the structure of a synaptic junction, and what happens there?

A

Structure: Includes the presynaptic terminal (axon), synaptic cleft (space between neurons), and postsynaptic membrane (receptor region on the receiving neuron).

Function: Electrical signals trigger neurotransmitter release from the presynaptic neuron, crossing the synaptic cleft and binding to receptors on the postsynaptic neuron, initiating a new electrical signal.

40
Q

What are mechanoreceptors, and how do they contribute to the sense of touch?

A

Merkel Cells: Detect light touch and texture; slow-adapting receptors.

Meissner’s Corpuscles: Sense light touch and low-frequency vibration; rapidly adapting.

Pacinian Corpuscles: Detect deep pressure and high-frequency vibration; rapidly adapting.

Ruffini Endings: Respond to skin stretch; slow-adapting.

41
Q

What is the cortical homunculus?

A

A distorted representation of the human body mapped onto the primary motor and sensory cortex. It reflects the density of nerve endings, where larger areas represent greater sensitivity (e.g., hands, lips).

42
Q

How does skeletal muscle contract, and what makes up the contractile unit?

A

Contractile Unit: The sarcomere, composed of actin (thin filaments) and myosin (thick filaments).

Mechanism: Calcium release triggers actin and myosin interaction, causing the sarcomere to shorten (sliding filament theory), producing muscle contraction.

43
Q

Describe the stages of heart contraction and relate them to the ECG.

A

Stages: Atrial contraction (P wave), ventricular contraction (QRS complex), and relaxation (T wave).

Relation to ECG: Each phase of the cardiac cycle corresponds to distinct waveforms on the ECG, reflecting electrical activity in the heart.

44
Q

What is the structure of a hepatocyte?

A

Hepatocytes are polygonal liver cells with a large nucleus and abundant mitochondria and ER, facilitating metabolism, detoxification, and protein synthesis.

45
Q

Describe the structure and function of intestinal villi

A

Structure: Finger-like projections in the small intestine lined with epithelial cells and containing capillaries and a lacteal for nutrient absorption.

Function: Increase surface area for efficient absorption of nutrients and transport to blood and lymph.

46
Q

What is the oxygen-hemoglobin saturation curve, and what factors can cause shifts?

A

Curve: Reflects hemoglobin’s affinity for oxygen at different partial pressures of oxygen.

Shifts: Right shift (decreased affinity) occurs with increased CO2, acidity, temperature, or 2,3-BPG; left shift (increased affinity) with opposite conditions.

47
Q

Q: What are the components and functions of the nephron, and name one intrinsic and one extrinsic regulatory factor?

A

Components: Includes the glomerulus (filtration), proximal tubule (reabsorption), loop of Henle (water/salt balance), distal tubule, and collecting duct (final reabsorption/secretion).

Intrinsic Factor: Tubuloglomerular feedback, which adjusts filtration rate based on salt concentration.

Extrinsic Factor: Hormonal regulation via aldosterone and antidiuretic hormone (ADH) to maintain water and electrolyte balance.

48
Q

What is the Frank-Starling law, and how does it affect heart function?

A

Concept: The Frank-Starling law states that the force of the heart’s contraction increases as the volume of blood filling the heart (end-diastolic volume) increases.

Mechanism: Stretching cardiac muscle fibers due to increased blood volume enhances cross-bridge formation between actin and myosin, leading to a stronger contraction and greater stroke volume.

Result: This mechanism ensures that the heart pumps out all the blood it receives, adapting to changes in venous return to maintain cardiac output

49
Q

How does the negative feedback loop involving baroreceptors help regulate blood pressure?

A

Detection: Baroreceptors, located in the carotid arteries and aorta, detect changes in blood pressure by sensing the stretch of blood vessel walls.

Response to High BP: When blood pressure rises, baroreceptors increase firing rate, signaling the brain (medulla) to decrease sympathetic activity and increase parasympathetic output. This lowers heart rate, reduces contractility, and dilates blood vessels, decreasing blood pressure.

Response to Low BP: If blood pressure drops, baroreceptors reduce firing rate, signaling the brain to increase sympathetic output. This raises heart rate, increases contractility, and constricts blood vessels, raising blood pressure.

Outcome: This feedback loop helps maintain stable blood pressure under varying conditions

50
Q

What are the primary roles of blood within the body?

A

Transport: Carries oxygen from lungs to tissues, carbon dioxide from tissues to lungs, nutrients from the digestive tract to cells, and waste products to kidneys for excretion.

Regulation: Helps regulate body temperature, pH levels, and fluid balance.

Protection: Contains immune cells (white blood cells) and antibodies that defend against pathogens, and platelets that facilitate clotting to prevent blood loss from injuries.

Homeostasis: Maintains stable conditions within the body, such as delivering essential elements for cellular function and removing metabolic byproducts

51
Q

Merkel’s receptor

A

Sustained touch

52
Q

Meissner’s

A

change in texture

53
Q

Ruffini

A

skin stretch

54
Q
A
55
Q

Glomerulus

A

A network of capillaries within Bowman’s capsule where blood filtration occurs. The high pressure in the glomerulus forces water, electrolytes, and small molecules into Bowman’s capsule, forming the filtrate

56
Q

Bowman’s Capsule

A

encases the glomerulus and is the site where blood filtration begins. It collects the filtrate that results from the filtration of blood, allowing small molecules, ions, and water to pass while retaining larger molecules like proteins and blood cells.

57
Q

Proximal Convoluted Tubule (PCT)

A

Responsible for the reabsorption of approximately 65-70% of the filtered sodium, chloride, and water. It also reabsorbs nutrients like glucose and amino acids, and secretes waste products such as hydrogen ions and certain drugs.

58
Q

Loop of Henle

A

Composed of a descending limb and an ascending limb. The descending limb is permeable to water but not to solutes, allowing water to be reabsorbed back into the bloodstream, concentrating the filtrate.

The ascending limb is impermeable to water but actively transports sodium, potassium, and chloride ions out of the filtrate, which helps to create a concentration gradient in the medulla.

59
Q

Distal Convoluted Tubule (DCT)

A

Involved in further sodium and chloride reabsorption and the regulation of potassium and hydrogen ion secretion. The DCT plays a crucial role in adjusting the pH of blood and electrolyte balance under hormonal influence (e.g., aldosterone).

60
Q

Collecting duct

A

Collects urine from multiple nephrons and is the site for final adjustments in water reabsorption, influenced by the hormone vasopressin (antidiuretic hormone, ADH). It also plays a role in the reabsorption of urea, contributing to the concentration of urine.

61
Q
A