1.1. Anaesthetics - Pain Flashcards
What is Pain?
An unpleasent Sensory and Emotional Experience associated with Actual / Potential Tissue Damage, or Described in terms of such Damage
With Regards to Treating Pain, what are the
- Physical benefits?
- Psychological benfits?
- a) Improved Sleep
- b) Better Appetite
- c) Fewer Medical Complications - M.I. / Pmeumonia
- a) Reduced Siffering
- b) Less Depression / Anxiety
With Regards to Treating Pain, what are the benefits for:
- The Family?
- Society?
- a) Improved functioning as a Family Member
- b) Able to keep working
- a) Lower Health Costs - Shorter Hospital Stays
- b) Able to contribute to the community
What are the Classifications of Pain under:
- Duration?
- Cause?
- Mechanism?
- Acute / Chronic / Acute on Chronic
- Cancer / Non-Cancer
- Nociceptive / Neuroathic
What is the difference between:
- Acute Pain?
- Chronic Pain?
- Pain of Recent Onset and probable Limited Duration
- Pain > 3 months / Lasting after normal Healing
Note - There is often no identifiable cause of Chronic Pain
What is the difference between:
- Cancer Pain?
- Non-Cancer Pain?
- Progressive - May be a mixture of Acute and Chronic
2. Many different causes - Acute or Chronic
What are the Features of Nociceptive Pain?
- Obvious Tissue Injury / Illness
- Protective Function
- Described as Well Localised and Sharp / Dull
Note - Also called Physiological / Inflammatory Pain
What are the Features of Neuropathic Pain?
- Nervous System Damage / Abnormality
- Tissue Injury may not be Obvious
- Does not have a Protective Function
- Described as:
- a) Burning, Shooting +/- Numbness / Pins and Needles
- b) Not Well Localised
What us the Physiology of Pain?
- Periphery = Tissue Injury - Chemical Release - Stimulation of Nociceptors - Signals in A-Delta / C Fibres
- Spinal Cord = Dorsal Horn - Nerve Synapse with Second Nerve - Ascend up opposite side of Spinal Cord
- Brain = Thalamus - Connection to Cortex / Limbic System / Brainstem - Pain Perception is in the Cortex
- Modulation - Descending Pathway (Brain - Dorsal Horn) - Decreases Pain signal
What is the Gate Theory of Pain?
Distraction Stimulus (Rubbing) Reduces pain by Inhibiton of Neurons
What is Neuropathic Pain?
Abnormal Processing of Pain Signal due to Nervous System Damage / Dysfunction, e.g.:
- Nerve Trauma
- Diabetic Pain
- Fibromyalgia
- Chronic Tension Headache
What are the Pathological Mechanisms for Neuropathic Pain?
- Increased Receptor Numbers
- Abnormal Sensitisation of Nerves - Peripheral / Central
- Chemical Changes in the Dorsal Horn
- Loss of Inhibitor Modulation
What are the Drug Classifications?
- Simple Analgesics - Paracetamol / NSAID’s
- Mild Opioids - Codeine / Morphine / Oxycodone / Fentanyl / Tramadol
- Antidepressants - Amitriptyline / Duloxetine
- Anticonvulsants - Gabapentin
- Ketamine - NMDA Receptor Antagonist
- Local Anaesthetics
- Topical Agents
What are the Treatments for Pain from the Periphery?
- Non-Drug Treatments - R.I.C.E.
- NSAID’s
- Local Anaestetics
What are the Treatments for Pain from the Spinal Cord?
- Non-Drug Treatments - Acupuncture / Massage / TENS
- Local Anaesthetic
- Opiods
- Ketamine