109 Flashcards

1
Q

What is the dose, vial and generalized mechanism/classification of dopamine?

A

Dose 1: IV 1.0 - 15 mcg/kg/min

Vial: 400mg/250ml (premixed bag)

Mechanism/Classification: Inotropic vasopressor”

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2
Q

What is the dose, vial and generalized mechanism/classification of vasopressin?

A

Dose: IV 0.02 to 0.04 Un/min (convert to per hour for pump)

Vial:

Mechanism/Classification: Arterial vasoconstriction, vasopressor

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3
Q

Define synergism

A

The result of two medications is greater than each individual one

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4
Q

What is the dose, vial and generalized mechanism/classification of lorazepam (ativan)?

A

Dose: IV/PO: 0.5 - 4.0 mg/dose

Vial: ?

Mechanism/Classification: Benzodiazepine

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5
Q

What is the dose, vial and generalized mechanism/classification of propofol?

A

Dose 1: IV 2.0-2.5 mg/kg

Dose 2: IV 5.0-100 mcg/kg/min

Vial: 1000 mg/100 ml

Vial: 500 mg/50 ml

Mechanism/Classification: General anaesthetic

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6
Q

What is the dose, vial and generalized mechanism/classification of succinylcholine?

A

Dose: 1.0 to 1.5 mg/kg

Vial: 200 mg/ 10 ml

Mechanism/classification: Depolarizing neuromuscular blocking agent/Paralytic

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7
Q

Define iatrogenic response

A

A response in the patient that was the result of a treatment by the practitioner

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8
Q

What is the dose, vial and generalized mechanism/classification of dobutamine?

A

Dose: IV 2.5-20 mcg/kg/min

Preparation: 250mg in 20ml

Mechanism/Classification: Direct B1 (+++) and B2 (+) agonist inotrope

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9
Q

What is the dose, vial and generalized mechanism/classification of fentanyl?

A

Dose 1: IV 25 - 100 mcg/dose

Dose 2: IV 1.0 - 2.0 mcg/kg/hr

Dose 3: IN 2 mcg/kg

Vial: 250 mcg/5 ml

Vial: 100 mcg/2 ml

Mechanism/Classification: Opioid analgesic

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10
Q

Define idiosyncrasy

A

A abnormal reaction to a drug

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11
Q

What is the dose, vial and generalized mechanism/classification of norepinephrine?

A

Dose 1: IV 2mcg/min to 12mcg/min or

Dose 2: IV 0.01mcg/kg/min to 3mcg/kg/min

Vial: 4mg/4ml

Mechanism/Classification: Inotropic vasopressor (Alpha+++ B1++)

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12
Q

Give examples of the following classifcations of medications:

Sympathomimetics

Statins

Steroids

Antihypoglycemic

Antifibrinolytics

Eletrolytes

Uterotonics

PPI

Vitamins

Tocolytics

Antiemetics

Platelet inhibitors

A

-Sympathomimetics - Dopamine, Epinephrine, Norepinephrine, Dobutamine-

Statins - simvastatin, rosuvastatin, atorvastatin-

Steroids - Hydrocortisone, dexamethasone, prednisone, solumedrol-

antihypoglycemic - glucagon-

antifibrinolytics - txa-

Electrolytes - calcium gluconate/chloride, magnesium sulfate, KCl, Sodium bicarbonate-

Uterotonics - Oxytocin, Prostaglandin E2, -

PPI - Pantoprazole, Omeprazole, Rabeprazole-

Vitamins - Hydroxycobalamin, Thiamine-

Tocolytics (stop labour) - indomethacin, Nifedipine (Adalat), Terbuataline-

Antiemetics - Diphenhydramine, Ondasetron, Maxaran

Platelet inhibitors - asa, clopidogrel (plavix), Ticagralor (Brilinta), Prasrugrel

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13
Q

What is the dose, vial and generalized mechanism/classification of phenylephrine?

A

Dose 1: IV 50-100mcg/dose

Dose 2: IV 0.4 to 9.1 mcg/kg/min

Vial 1: 500mcg/10ml preload syringe

Vial 2: 10mg/1 ml

Mechanism/Classification: direct alpha adrenergic agonist, vasopressor

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14
Q

Define Cumulative effect

A

When after several doses of a med are given or it absorbs faster than it was eliminated

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15
Q

What is the dose, vial and generalized mechanism/classification of rocuronium?

A

Dose 1: IV 0.6 to 1.2 mg/kg

Vial: 50mg / 5ml

Mechanism/Classification: Non-depolarizing neuromuscular blocker/paralytic, blocks acetylcholine receptor sites

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16
Q

Define summation effect

A

When multiple medication are required to produce an effect when one alone would not have done so

17
Q

Define tachyphylaxis

A

When a patient rapidly becomes tolerant of a medication

18
Q

Define therapeutic index

A

Ratio of LD50 of population to its effective dose 50%; medication margin of safety

19
Q

What is the dose, vial and generalized mechanism/classification of haloperidol?

A

Dose 1: IM 2.0 - 5.0 mg/dose

Dose 2: IV 5.0-20mg (25% of this q 6 hours)

Vial: 5 mg/ 1 ml

Mechanism/Classification: Neuroleptic/Antipsychotic

20
Q

Define potentiation

A

Where one medication increases the effect of another one

21
Q

What is the dose, vial and generalized mechanism/classification of ketamine?

A

Dose 1: IV 0.5-2.0 mg/kg

Dose 2: IV 1.0-2.0 mg/min

Vial: 500 mg/10 ml

Vial: 100 mg/2 ml

Mechanism/Classification: Dissociative anaesthetic (NMDA receptor antagonist)

22
Q

What is the dose, vial and generalized mechanism/classification of milrinone?

A

Dose 1: IV 50 mcg/kg

Dose 2: IV 0.5 mcg/kg/min (max 1.13mg/kg/24 hrs)

Vial: ??

Mechanism of action: PDE Inhibitor (Pure inotropy)