10.2 Pelvic Inflammatory disease Flashcards

1
Q

What is PID and what is it a result of?

A

Pelvic Inflammatory Disease: results from an ascending infection of the females upper genital tract (spreads upwards from endocervix)

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2
Q

List 4 conditions PID can lead too and state what each is

(Hint: can lead to an infection of EVERY part of female genital tract)

A

1) Endometritis: Inflammation of endometrium
2) Salpingitis: Inflammation of fallopian tubes
3) Parametritis: Inflammation of pelvic floor connective tissue aka “pelvic cellulitis”
4) Oophoritis: Inflammation of ovary
5) Tubo-ovarian abscess: abscess (collection of pus) of the fallopian tube and/or the ovary
6) Pelvic peritonitis: inflammation of the peritoneum (emergency!)

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3
Q

Give 4 common symptoms of PID

A

1) pelvic pain
2) lower abdominal pain (usually bilateral)
3) deep dysparenunia
4) abnormal vaginal bleeding
5) abnormal vaginal discharge
6) RUQ pain
7) secondary dysmenorrhoea

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4
Q

Give 4 gynaecological differentials for lower abdominal pain

A
  1. ectopic pregnancy
  2. endometriosis
  3. ovarian cyst rupture
  4. ovarian torsion
  5. mittleschmerz pain (mid-cycle cramping due to ovulation)
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5
Q

Give 2 GI differentials for for lower abdominal pain

A
  1. Irritable bowel syndrome
  2. diverticular disease
  3. apendicitis
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6
Q

Give one renal differential for lower abdominal pain + one other

A

Renal: UTI (especially if pain is bilateral)

Other: Functional pain (if there is no known cause)

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7
Q

Give 4 risk factors for development of PID

(Hint: same as STI risk factors)

A
  1. young <25 years
  2. early age first coitus
  3. multiple partners
  4. new partner < 3 months
  5. history of STIs (either patient or partner)
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8
Q

Give 4 infectious causes of PID (most common)

A

1) Chlamydia (most common)
2) Gonorrhoea
3) Mycoplasma genitalium
4) Pathogens in normal vaginal flora (anaerobes, G vaginalis, H influenze)

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9
Q

List 4 things you may look for on examination in patient with suspected PID

A
  1. lower (usually bilateral) abdominal tenderness
  2. cervical or uterine tenderness
  3. abnormal cervical or vaginal mucopurulent discharge (spectulum)
  4. fever >38 degrees (but may be afebrile)
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10
Q

List 4 investigations that can be done for suspected PID + explain why?

A

1) Pregnancy test to rule out ectopic pregnancy or threatened abortion
2) Triple swabs (high vaginal, endocervical and endocervical NAAT) to test for gonorrhoea, chlamydia and other bacteria infections
3) Bloods: check ESR, CRP, leucocyte count (raised levels support PID but are not specific). Also test bloods for HIV and Syphilis
4) Transvaginal ultrasound to check for hydrosalpinx or an abscess
5) CT/MRI to exclude other diagnoses

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11
Q

What are Emperical antibiotics?

A

antibiotics given to a person before the specific bacterium or fungus causing an infection is known (before swab returns)

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12
Q

How would you treat PID before admitting to hospital + what else MUST you do?

A

Treatment pre-admission: analgesias and empirical antibiotics (usually ceftriaxone, doxycycline, metronidazole)

MUST also refer to GUM clinic for contact tracing and review patient after 72 hours

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13
Q

When should you consider hsopital admission or alternative diagnosis and why?

A

After 72 hours If there little-no improvement, consider admission or alternative diagnosis.

This is because surgery (laproscopic) may be requiredif there is no response to antibiotics, a tubo-ovarian abscess or increasing severity

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14
Q

What is meant by “admission criteria” and 5 reasons for immediate admission of RUQ pain

A

Admission criteria: deciding whether patient needs to be treated as inpatient or outpatient when they present.

If any of the following apply they should be admitted immediately:

  • can NOT exclude an ectopic pregnancy
  • can NOT exclude another surgical emergency (eg. appendicitis)
  • can NOT tolerate oral medications
  • have severe signs and symptoms (febrile, nausea, vomiting etc)
  • suspected pelvic peritonitis (tenderness in abdomen on soft touch)
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15
Q

If antibiotics are prescribed what is IMPORTANT to inform patient?

A

Explain the importance of completing entire course of antibiotics (even if swabs are negative)

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16
Q

If patient says they have had an IUD put in within the last 4-6 weeks what should you consider and when?

A

IUD removal

  • If patient requests it
  • If no improvement after 72 hours
  • consider interim emergency oral contraception

Recent IUD can cause PID

17
Q

If the cause of lower abdominal pain is found to be an STI what other 2 things should be considered alongside treatment?

A

1) Partner treatment: current and recent <6 months + contact tracing
2) Test of cure, isnt always done but should be if:

  • Initial swabs (+) for chlamydia or gonorrhoea
  • symptoms persist after treatment
  • poor compliance suspected
  • possibility of reinfection
18
Q

Give 4 complications of PID and how you would reduce chance of these occuring?

A
  • Tubal infertility
  • Ectopic pregnancy
  • Chronic pelvic pain
  • Tubo-ovarian abscess

Give prompt empirical antibiotics to reduce chances of these complications!

19
Q

What is Fitz-Hugh-Curtis and what causes it?

How is it thought that this occurs (3)

A

It is a form of Perihepatitis. It is infection of the liver capsular without hepatic parenchyma involvement due to Intra-abdominal spread of PID. The way this occurs is unknown but could be due to:

  • fluid spread along paracolic gutter
  • lymph flow
  • blood flow
20
Q

Desribe presentation of Fitz-Hugh-Curtis

A

May be asymptomatic and found incidentally at surgery ➞ violin string like adhesions on liver. Or may be symptomatic and can be split into acute and chronic

1) acute phase symptoms incl:

  • sharp severe RUQ pain
  • right shoulder tip involvement (due to irritation along the diaphragm)
  • systemically unwell: fever, nausea, vomiting, etc

2) chronic phase may include a persistent dull RUQ pain

21
Q

How would you diagnose and treat Fitz-Hugh-Curtis

A

Diagnosis

  1. Bloods: for raised inflam markers and normal LFTs (b/c parenchyma of liver is NOT involved)
  2. Ultrasound to exclude biliary stones (may be able to see violin string like adhesions on the anterior abdominal wall and diaphragm)

Treatment: antibiotics