10.2 - Kidney and Water Flashcards
What is the stimulus for hypothalamus in kidney and water?
Hypothalamus detects an INCREASE in solute concentration in blood ( low [water] )
What does hypothalamus do when it has this stimulus?
- Directs posterior pituitary to release ADH (anti-diuretic hormone) into the blood
What does ADH do?
Targets collecting ducts of nephron, to be directed to REABSORB more water back into the blood (less water in urine!)
-> this lowers [solute] in blood
What is the negative feedback of the ADH process?
Hypothalamus detects decrease in [solute] and direct posterior pituitary gland to stop releasing ADH
What is an anti-diuretic?
Causes H2O reabsorption in collecting duct
Examples of diuretics and what they do
Diuretic: releases more urine to decrease blood pressure
Examples: alcohol, coffee
What does diabetes insipidus do?
Insufficient release of ADH from pituitary (acts as diuretic)
Role/process of ADH when: salt eaten/too much sweating
- water content in blood is low
- brain releases a lot of ADH
- high volume of water reabsorbed by kidney
- small volume of CONCENTRATED urine passed to bladder
- high volume of water passes into blood
Role of ADH when: too much water is drunk
- Water content of blood is too high
- Brain releases little ADH
- Low volume of water reabsorbed by kidney
- High volume of DILUTE urine passed to bladder
- Low volume of water passes into blood