1010 Flashcards
transgenic
refers to an organism that carries one or more genes from a different species
protein
a macromolecule made up of repeating subunits known as amino acids, which determine the shape and function of a protein. Play critical roles in living organisms.
Amino acids
building blocks of proteins. 20 different types
gene
a sequence of DNA that contains the information to make at least one protein
gene expression
process of using DNA instructions to make proteins
genotype
genetic make up of an organism
phenotype
physical attributes of an organism, including both observable and internal or non- observable traits
alleles
alternative versions of the same gene that have different nucleotide sequences
regulatory sequence
part of the gene that determines the timing, amount, and location of protein produced
coding sequence
part of a gene that specifies the amino acid sequence of a protein. Determines identity, shape and function of proteins
genetically modified organism
organism that has been genetically altered by humans
gene therapy
type of treatment that aims to cure disease by replacing defective genes with functional ones
transcription
first stage of gene expression, during which cells produce molecules of messenger RNA (mRNA) from instructions encoded within genes
translation
second stage of gene expression, “reads” mRNA sequences and assembles the corresponding amino acid to make a protein
messenger RNA
RNA copy of an original DNA sequence made during transcription
RNA polymerase
enzyme that accomplishes transcription. copies a strand of DNA into a complementary strand of mRNA
ribosome
cellular machinery that assembles proteins during the process of translation
codon
sequence of three mRNA nucleotides that specifies a particular amino acid
transfer RNA
type of RNA that helps ribosomes assemble chains of amino acids during translation
anticodon
part of a tRNA molecule that binds to a complementary mRNA codon
genetic code
particular amino acid specidied by particular mRNA codons
tissue
organized group of different cell types that work together to carry out a particular function
stem cells
immature cells that can divide and differentiate into specialized cell types
adult stem cells
(somatic stem cells) stem cells located in tissue that hep maintain and regenerate those tissue
cellular differentiation
process by which a cell specializes to carry out a specific role
differential gene expression
process by which genes are “turned on” (expressed) in different cell types
multipotent
describes a cell with the ability to differentiate into a limited number of cell types in the body
embryonic stem cells
stem cells that make up an early embryo, which can differentiate into nearly every cell type of the body
blastocyst
stage of embryonic development in which the embryo is a hollow ball of cells. Researchers can derive embryonic stem cell lines during this stage
pluripotent
describes a cell with the ability to differentiate into nearly any cell type in the body
totipotent
describes a cell with the ability to differentiate into any cell type in the body
induced pluripotent stem cell
pluripotent stem cell that was generated by mainpulation of a differentiated somatic cell