100814 cardiomyopathy

Question 1

cardiomyopathy definition

Answer 1

heart disease resulting from abnormality in myocardium

produces abnormalities in cardiac wall thickness, chamber size, mechanical and/or electrical dysfxn

Question 2

primary cardiomyopathy

Answer 2

confined to heart muscle

Question 3

secondary cardiomyopathy

Answer 3

myocardial involvement as a component of systemic or multiorgan disorder

Question 4

dilated cardiomyopathy

Answer 4

progressive cardiac dilation

systolic dysfxn

Question 5

what are the consequences possible of dilated cardiomyopathy?

Answer 5

heart failure
thrombi
regurgitation (due to ventricular dilation)

Question 6

what can acute viral myocarditis cause in terms of cardiomyopathy?

Answer 6

dilated cardiomyopathy

Question 7

what agents can cause acute viral myocarditis?

Answer 7

coxsackie B
echovirus

causes self-limited infection

Question 8

what cardiomyopathy does iron overload cause?

Answer 8

dilated cardiomyopathy

Question 9

what cardiomyopathy does alcohol cause?

Answer 9

dilated cardiomyopathy (alcohol has direct and indirect toxic effects)

Question 10

doxorubicin can cause what kind of cardiomyopathy?

Answer 10

dilated

Question 11

what type of cardiomyopathy is peripartum cardiomyopathy?

Answer 11

dilated

Question 12

when does dilated cardiomyopathy occur in the case of peripartum cardiomyopathy?

Answer 12

late in pregnancy or several weeks to months postpartum

Question 13

gross morphology of dilated cardiomyopathy

Answer 13

4 chamber dilatation
variable wall thickness (normal, hypertrophy, flabby)
mural thrombi
normal valves
mitral or tricuspid regurgitation may be present due to dilation of chamber

Question 14

histology for dilated cardiomyopathy

Answer 14

not specific (except for iron overload)

hypertrophy and fibrosis are usual

Question 15

prognosis of dilated cardiomyopathy

Answer 15

depends on etiology