10. Pharmacology Flashcards

1
Q

effects of NSAIDs

A
  • Analgesic
  • Anti-inflammatory
  • Anti-pyretic
  • Anti-coagulant
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Dose for ibuprofen

A

400 mg 3x daily

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Dose for naproxen

A

550mg 2x per day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Dose for Diclofenac

A

50 mg 2x/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Dose for diflunisal

A

500mg 2x/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Avoid NSAIDs in patients with

A
  • Renal disease
  • Asthma
  • GI ulcers
  • Late stage pregnancy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Side effects of NSAIDs

A

Common

  • GI issues
  • Somnolence
  • Rash
  • Headache

Rare

  • Ulcers
  • CV events
  • Erythema Multiforme
  • Coagulopathy
  • Anaphylaxis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the selective COX 2 inhibitors and their doses

A

Celecoxib- 200 mg 2x/day

Etodoloc - 200 mg 2x/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Side effects of Cox-2 inhibitors

A

Common

  • GI issues
  • Malaise
  • Rash
  • Headache

Rare

  • CV events
  • Erythema multiforme
  • GI ulcers
  • Steven johnson syndrome
  • Hepatitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Selective COX-2 inhibitors should be avoided in

A
  • CV disease
  • Pregnancy
  • Allergy to Sulpha drugs
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Effects of acetaminophen

A
  • Analgesic

- Anti-pyretic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Dose of acetaminophen

A
  • 500-1000mg (4x/day- 3x/day)

- Max dose= 3 g/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Acetaminophen should be avoided in patients…

A
  • Liver disease (hepatotoxic)

- Chronic alcoholics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Effect of corticosteroids

A
  • Anti-inflammation
  • Anti-pyretic
  • Analgesia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Common cortical steroids and their dose

A
  • Methyl prednisone (4mg)

- Dexamethasone (2-4 mg 2x/day)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Corticosteroid side effects

A

Common

  • GI issues
  • Mood changes
  • Somnolence
  • Headache
  • Rash

Rare

  • Ulcers
  • CV events
  • Erythema multiforme
  • Hypertension
  • Diabetes
  • Hepatitis
  • Osteoporosis
  • Cushing Syndrome
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Corticosteroids should be avoided in

A
  • Renal disease
  • Asthma
  • GI ulcers
  • Late stage pregnancy
18
Q

Max dose of lidocaine 2%

A

4mg/kg (max= 300 mg)

19
Q

Max dose of bupivacaine 0.5%

A

0.6 mg/kg (max= 90 mg)

20
Q

Side effects of LA

A

Common

  • Edema
  • Erythema
  • Petechial rash
  • Neuromuscular weakness

Rare

  • Confusion
  • Agitation
  • Tremors
  • Bradycardia
  • Respiratory depression
  • Palpitations
21
Q

LA is avoided in patients with

A

myositis

22
Q

Commonly prescribed opioids and their dose

A
  • Codeine 30 mg 4x/day
  • Hydrocodone 10 mg 4x/day
  • Morphine 30 mg 2x/day
23
Q

Side effects of opiods

A
  • GI effects (dry mouth and constipation)
  • Respiratory depression
  • Neuro-cognitive effects
24
Q

T/F Muscle relaxants are given by the dentist to treat pain

A

F- they modulate don’t don’t treat the pain. Modulate pain by acting centrally.

25
Q

What are the difference muscle relaxants and their dose

A

Cyclobenzaprine 10 mg before bed (hs)
Baclofen 10 mg before bed (hs)
Tizanidine 4 mg 2x/day

26
Q

Side effects of muscle relaxants

A

Common

  • Mastication muscle pain
  • Muscle pain upon awakening
  • Sleep disturbance associated with pain

Rare

  • Hallucinations
  • Organ toxicity
  • Seizures
27
Q

Cyclobenzaprine is contraindicated in what patients

A

recent MI

28
Q

Commonly perscribed benzodiazepines are and their dose

A
  • Clonazepam 0.5 mg before bed

- Diazepam 2.5 mg before bed

29
Q

Commonly used TCAs and their dose

A
  • Amitriptyline 10-25 mg before bed

- Nortriptyline 25 mg before bed

30
Q

Side effects of TCAs

A
  • Gi issues
  • Somnolence
  • Dizziness
  • Cardiac arrhythmia
  • Hypoglycemia
31
Q

Common NMDA receptor antagonists and their dose

A
  • Ketamine 2 mg/kg IM

- Dextromethophan 80 mg

32
Q

Side effects of NMDA receptor antagonists

A

Common

  • GI events
  • Somnolence
  • Confusion
  • Respiratory depression

Rare

  • Dizziness
  • Nervousness
  • Restlessness
33
Q

What are the different anti-convulsant medications

A
  • Carbamazepine
  • Oxcarbazepine
  • Gabapentin
  • Pregabalin
34
Q

Dosing for carbamazepine

A
  • Start at 100 mg/day

- Increase 100 mg every 2 days to max 1200 mg/day

35
Q

Side effects of carbamazepine

A

Common

  • Dizziness
  • Unsteady
  • Nausea and anorexia

Rare

  • Aplastic anemia
  • Elevation of liver enzymes
  • Leukopenia
36
Q

Dose of oxcarbazepine

A
  • Start at 300 mg 2x/day

- Increase 300 mg every 3 days to max 1800-2400 mg/day

37
Q

Side effect of oxcarbazepine

A

Common

  • Dizziness
  • Nausea
  • Diplopia
38
Q

Dose of gabapentin

A
  • 300 mg/day 100 mg 3 times a day

- max= 3600/day

39
Q

Side effects of Gabapentin

A
  • Peripheral edema
  • Dizziness
  • Nausea
  • Fatigue
40
Q

Dose of pregabalin

A
  • 150 mg/day (start)

- Max= 300 mg/day

41
Q

Side effects of pregabalin

A
  • Dizziness
  • Somnolence
  • weight gain
  • Peripheral edema
42
Q

Adverse effects of capsaicin

A
  • Local burning sensation
  • GERD
  • Contact dermatitis