10 Coordination Flashcards
The nervous system uses…
nerve cells to pass electrical impulses along their length
The nervous system stimulates
target cells by secreting neurotransmitters onto them
Nervous communication is…
- rapid
- short-lived
- localised
Hormonal system produces…
chemicals that are transported in blood plasma
Hormonal communication is…
- slower
- long lasting
- widespread
Chemical mediators are…
chemicals released from cells that have an effect on cells in the immediate vicinity
two examples of chemical mediators
histamine
prostaglandins
Histamine is released…
following injury or in response to an allergen
Histamine causes…
dilation of small arteries/arterioles
increased capillary permeability
localised swelling, redness and itching
prostaglandins are found…
in cell membranes
prostaglandins cause
dilation of small arteries/arterioles
changes in blood pressure and neutrotransmitters
prostaglandins affect
pain sensation
Plants do not have…
a nervous system
Plants must respond to…
light
gravity
water
Plants respond to external stimuli by
plant growth factors
Plant growth factors… (3)
- exert influence by affecting growth
- made by cells throughout the plant rather than organs
- some affect the tissues that release them
Example of a plant growth factor and its effect…
IAA -indoleacetic acid
causes plant cells to elongate
Response to light directed at a shoot from one side (6)
- tip cells produce IAA which is transported down the shoot
- initially transported to all sides as it moves down
- light then causes IAA to move towards the shaded side
- IAA builds up on the shaded side
- IAA elongates cells so cells on shaded side grow more
- they grow faster so the shoot bends towards the light
IAA … growth in root cells
decreases
Neurones…
are specialised cells adapted to rapidly carrying nerve impulses from one part of the body to another
Six key parts of neurones
- cell body
- dendrons
- axon
- Schwann cells
- myelin sheath
- nodes of Ranvier
Neurone cell body contains…
nucleus and large amounts of rough ER (for neurotransmitter production)
Dendrons are…
extensions of the cell body that subdivide into smaller branched fibres
Dendrons carry…
nerve impulses towards the cell body
Axon is..
a single long fibre
that carries nerve impulses away from the cell body
Schwann cells…
surround the axon
protecting and insulating it
A myelin sheath
forms a lipid rich covering to the axon
Nodes of ranvier are…
gaps between adjacent Schwann cells where there is no myelin sheath
Sensory neurones (3)
- transmit impulses from a receptor to an intermediate/motor neurone
- one dendron carries impulse towards cell body
- one axon carries impulse away from cell body
Motor neurones (2)
- transmit impulses from an intermediate/sensory to an effector
- long axon and many short dendrties
Intermediate neurones (2)
- impulses between neurones (sensory to motor etc)
- numerous short processes
Define nerve impulse
a self-propagating wave of electrical activity along the surface of the axon membrane
Three ways movement of Na+ and K+ across the membrane is controlled
- phospholipid bilayer prevents diffusion across
- ion channels, gated/non gated control ion movement
- Sodium-potassium pump controls active transport of Na+ out and K+ in
Sodium-potassium pump
actively transports potassium into the axon and sodium out of the axon
The resting potential is usually
-65mV
The resting potential is caused by…
- 3Na+ actively transported out with 2K+ actively transported in to the axon. So more Na+ out than in.
- Na+ diffuse back into axon, K+ diffuse back out.
- But more K+ gates open, so they diffuse out faster.
- So even more positive ions out than in
At resting potential, chemical and electrical gradients are balanced when…
- Positively charged outside makes movement of Na+/K+ out difficult
When a stimulus is received, an action potential
causes a temporary reversal of axon membrane charges (depolarisation)
Depolarisation occurs because…
Channels in axon membrane open/close, causing ion movement.
7 steps of action potential
- Resting potential, some K+ channels are open but K+ closed.
- Stimulus, causes Na+ channels to open and Na+ diffuses in, trigger reversal
- More Na+ channels open, more diffusion into axon
- +40mV; Na+ channels close and K+ channels open.
- More K+ channels open, diffusing out and repolarising membrane
- Hyperpolarisation, then
- K+ channels close and Na+/K+ pump operates again (repolarisation)
The resting potential is maintained by…
active transport of Na+/K+ ions
The size of an action potential…
remains the same from one end of axon to another
One region of depolarisation acts as…
a stimulus for depolarisation of the next region
At resting potential…
the Na+ concentration outside axon is high relative to inside
the K+ concentration outside axon is low relative to inside
therefore the axon membrane is overall negative compared to the outside
A stimulus causes…
- a sudden influx of Na+ ions therefore a reversal of charge on the axon
- the membrane is therefore depolarised
The influx of sodium ions into the axon causes…
the opening of Na+ channels further along the axon, depolarising it
Behind the region of depolarisation, the Na+ voltage-gated channels…
close and K+ channels open
K+ leaves the axon along an electrochemical gradient
The region behind the action potential returns to its charged state when…
the K+ ion movement has continued to the extent that the axon membrane is now negative with respect to the inside
Repolarisation of the neurone allows…
Na+ ions to be actively transported out, returning the neurone to its resting potential.
In myelinated axons, the myelin sheath acts as…
an electrical insulator, preventing action potentials forming
In a myelinated neurone, action potentials occur only at…
the Nodes of Ranvier
The process of an action potential jumping from node to node is…
saltatory conduction
The speed of an action potential along a myelinated neurone is…
faster than an unmyelinated neurone
Factors affecting the speed of a nerve impulse
- myelination
- diameter of the axon
- temperature
The greater the diameter of an axon…
the faster speed of conductance as fewer ions leak from the axon
A higher temperature affects the speed of a nerve impulse how?
ions diffuse faster at higher temperatures
enzymes of respiration function faster to produce ATP for active transport
The refractory period occurs when…
Na+ voltage-gated channels are closed so a new action potential cannot be generated
Purposes of the refractory period: (3)
- ensures propagation in one direction only
- ensures discrete impulses as they are separated
- limits number of action potentials
The all-or-nothing principle means…
below the threshold value, no action potential is generated
above the threshold value, an action potential is generated
How is strength of stimulus detected?
Larger stimulus may create more impulses
Different neurones with different threshold values
A synapse is…
the point where the axon of one neurone connects with the dendrite of another, or with an effector.
Synapses transmit impulses by releasing…
neurotransmitters
The synaptic knob…
contains many mitochondria and endoplasmic reticulum to manufacture neurotransmitter
Neurotransmitter is stored in…
the synaptic vesicles
Once neurotransmitter is released…
it diffuses across the synaptic cleft to receptor molecules on the postsynaptic neurone
Synapses act as junctions, allowing
- a single impulse to be transmitted to different neurones to produce different responses simultaneously
- impulses to be combined to produce a single response
neurotransmitter is made only…
in the presynaptic neurone
Unidirectionality means…
synapses can only pass impulses in one direction
Spatial summation is…
-a number of presynaptic neurones simultaneously release neurotransmitter to exceed the threshold value, triggering an action potential
temporal summation means…
a single presynaptic neurone releases neurotransmitter many times to exceed the threshold value and trigger an action potential
Inhibition causes…
Cl- channels to open and hyperpolarise the membrane, making it less likely an action potential will be created
Cholinergic synapses have neurotransmitter,
acetylcholine
Cholinergic synapses occur…
in the central nervous system and at neuromuscular junctions
6 steps of cholinergic synapse transmission
1) action potential causes Ca2+ to enter presynaptic knob
2) Ca2+ causes vesicles to move and fuse with presynaptic membrane, releasing Ach into the cleft
3) Ach fuses with receptor sites on the Na+ ion channels, causing them to open and Na+ to diffuse in rapidly
4) Na+ influx depolarises membrane, causing an action potential
5) Acetylcholinesterase acts on Ach, breaking it up and causing it to diffuse back into presynaptic neurone.
6) ATP recombines the choline and ethanoic acid back to Ach, which is stored in vesicles. Na+ channels close when no Ach.
Two main forms of communication in mammals
Nervous system
Hormonal