10- commonly used therapeutics in skin disease Flashcards
Give 3 factors/ uses of therapeutics in skin disease
Kill/ repel parasites
control microbial inf
control inflammation/ pruritus
moisturise/ improve skin barrier
resolve scale
treat otitis externa
What is an emollient
Soften, lubricates, soothes skin
Often occlusive > seals in water content of stratum corner)
Animal/plant-oil based
How do moisturises work
Increases water content of stratum corner (draws water in)
Which topical treatment is very drying
Chlorhexidine
What is a anti-seborrhoeic agent
controls scale
what are the 2 actions of anti-seborrhoeic agents
Keratolytic
Keratoplastic
What do keratolytic agents do
reduce cohesion between cells of stratum corneum
What do keratoplastic agents do
restore normal epidermal epithelialisation and keratinisation
reduce epithelial turnover
What are the 2 forms of products we treat otitis external with?
Polypharmacy ear drops/creams
&
Ear cleaner
Components of a polypharmacy eardrop/cream
Antibiotic, antifungal & corticosteroid
Name 3 things you select a ear drop/cream based on
Organism present
Level of inflammatory activity require
Potential for ototoxicity if tympanic membrane is ruptured
Nature of exudate
Frequency of application
What antibiotic is inactivated by pus
Polymixin B
which out of prednisolone, mometasone and hydrocortisone has the lowest potency glucocorticoid
hydrocortisone
Give an advantage of using topical skin therapy
Decreased side effects compared to systemic
direct delivery to skin
allows you to target therapy
Give 2 disadvantages of using topical skin therapy
labour-intensive
some animals will not tolerate
hair may impede access to skin
possible toxicity if licked off
