10. Biological Approach To Treating OCD Flashcards
What does SSRI stand for?
Selective serotonin reuptake inhibitor
What does drug therapy do to the brain?
Increases or decreases levels of neurotransmitters
What is the standard treatment for symptoms of OCD?
SSRI antidepressants
What system do SSRIs work on?
Serotonin system
Where is serotonin released from?
Presynaptic neurons
What does serotonin travel across in the brain?
Synapses
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS
A03 reductionist
therapies also work as treatment meaning this cannot just be a biological response
What are the effects of snris
clomipramine can cause weight gain, erectile problems and changes in blood pressure and heart rhythm
Goldacre
goldacre
- studies are sponsored by drug companies and they overemphasise positive results and do not publish results where the drugs are not effective
explain how serotonin is absorbed in the brain:
released by presynaptic neuron and travels across a synapse
neurotransmitter chemically conveys signal from pre-postsynaptic neuron
reabsorbed by presynaptic neuron and reused
what do SSRI’S prevent?
the re-absorbtion and breakdown of serotonin
What are the results of SSRI ?
ssri’s effectively increase it’s levels in the synpase and thus continue to stimulate the postsynaptic neuron.
what SSRI drug is usually given to patients ?
Fluoxetine
how long do SSRI drugs take to become effective?
3-4 months of daily use
why are drugs more effective with CBT on OCD?
reduce emotional symptoms so patient can engage more
what are 2 alternatives to SSRIs?
tricyclics
SNRIs
what are tricyclics?
older antidepressant (Clomipramine) kept reserved for patients who don't respond to SSRIs
what are SNRIs?
serotonin-noradrenaline reuptake inhibitors (increase levels of serotonin as well as noradrenaline neurotransmitter)
why do many doctors and patients favour drug treatments over psychological treatments?
more cost-effective
non-disruptive to patients’ lives
what are some side effects of SSRIs?
blurred vision, loss of sex drive, indigestion (temporary)
why are drug side-effects a limitation?
reduces effectiveness as patients stop taking them
What did Soomro et al find? (2009)
studies showed better results for SSRI results compared to placebo conditions
how many patients taking SSRIs do symptoms decrease for?
70%
A03- comparison with CBT
less effort required
- less time taken
- cheaper for NHS