10/21 CVA Exam, eval Flashcards
Transient Ischemic Attack
Transient episode of neurological dysfunction
Temporary disturbance in blood supply to the brain, spinal cord or retina without permanent death of tissue.
Symptoms usually last ≤ 1 hour.
3-17% 90-day risk of a completed stroke.
Up to 50% occur within 48 hours of the TIA.
Stroke definition
Disruption of the vascular supply to the brain, brainstem or spinal cord that leads to infarction (death) of CNS tissue.
Stroke Classification
Ischemic (61 - 87%)
Thrombotic Vs Embolic
Large Vs Small vessel
Arterial Vs Venous
Hemorrhagic
Intraparenchymal Vs Subarachnoid
Primary Vs Secondary (conversion)
Higher proportion of hemorrhage in children
Large vessel thrombotic stroke
Slow, stuttering onset due to gradual occlusion +/- collateral circulation
Possibly preceded by TIA
Small vessel thrombotic “lacunar” stroke
Associated with longstanding hypertension and diabetes
Basal ganglia, internal capsule and brainstem
Cardioembolic Etiologies of ischemic stroke
Valvular atrial fibrillation Nonvalvular atrial fibrillation Acute myocardial infarction Bacterial endocarditis DVT with a patent foramen ovale Mitral valve prolapse Prosthetic mechanical heart valves Possible injury in multiple vascular distributions
Cerebral venous thrombosis
Relatively rare
Higher risk in peripartum period, OCPs + smoking, coagulopathies
Hemorrhagic Stroke
Fast, large volumes of blood
Increased mortality
If survived, decreased morbidity
Signs of hemorrhagic stroke
Vomiting, systolic BP >220 mm HG, severe headache, coma, decreased level of consciousness and progression over minutes-hours suggest hemorrhage.
Rapid deterioration in neurological status is common
Intraparenchymal Hemorrhagic Stroke
75% of hemorrhagic strokes
Hypertensive hemorrhages or Non-hypertensive hemorrhages
Hypertensive hemorrhage
Rupture of micro-aneurysms
Putamen»thalamus, pons, cerebellum and cerebral hemispheres.
Non-hypertensive hemorrhages
Sympathomimetic agents
Cavernous angiomas, amyloid angiopathy, intracranial tumors, bleeding disorders, trauma, vasculitis, hemorrhagic conversion, infection
Subarachnoid Hemorrhagic Stroke
25% of hemorrhagic strokes
Progressive deficits over minutes to hours
Headache and decreasing consciousness
Subarachnoid Hemorrhagic Stroke Etiology
Saccular aneurysms
Most common cause of SAH
45 % risk of death in the 1st 30 days - Most within a few days
Arteriovenous malformations (AVMs)
Emergency Medical Services Management of Stroke
Airway, breathing and circulation (ABC) Cardiac monitoring Intravenous access Oxygen, if needed Rapid identification of stroke/time of onset Rule out (and treat) stroke mimics Keep NPO (no food or drink) Alert receiving ED Rapid transport to closest appropriate facility
ED Evaluation During/Following Stroke
General medical examination Identify contributing factors: NIH Stroke Scale Glasgow Coma Scale Dysphagia screen Glucose Cardiac monitoring for 1st 24 hours
Medical Diagnosis of Stroke
Non-enhanced brain CT scan (NECT)
What is the gold standard for vascular evaluation during stroke?
Conventional angiogram
When is MRI better than NECT better for diagnosing stroke?
Acute small cortical strokes
Posterior fossa lesions
Acute vs. chronic lesions
Subclinical satellite lesions
Medical Treatment of Ischemic Stroke
Airway, breathing and circulation (ABC) Adequate hydration Treat elevated temperatures Glucose control Cardiac monitoring for 1st 24 hours Cautious initial approach to HTN Oxygen only if hypoxic Identify etiology of hypovolemia or hypotension
BP targets following stroke
If given TPA, < 185/110
If no TPA, < 220/120
Medical Treatment of Hemorrhagic Stroke
Airway, breathing and circulation (ABC) Rapid transport Immediate imaging Careful blood pressure management Normalize fluid balance and electrolytes Control seizures Normalize body temperature Correct any bleeding disorders (specific to the problem) DVT prophylaxis Clot evacuation and ventricular drainage as required