1. Vascular (Aortic pathology) Flashcards
Acute aortic syndrome - types (3)
Aortic dissection,
Intramural haematoma,
Penetrating Ulcer
Aortic dissection - trivia (2)
Commonest cause of acute aortic syndrome (70%),
Most commonly caused by hypertension (70%)
Aortic dissection - types (4)
Acute (<2 weeks) or chronic.
Location:
Stanford A (75%) - involve ascending aorta and arch proximal to left subclavian. Needs surgical Rx.
Stanford B - Distal to left subclavian. Treated medically unless complications (e.g. organ ischaemia)
Aortic dissection - causes (6)
Hypertension is most common.
Marfans,
Turners (aortic valve defects),
Infection,
Pregnancy,
Cocaine use.
Aortic dissection - imaging (4)
Non-contrast: Displacement of intimal calcifications.
Contrast:
- Intimal flap seen in 70%
- 2 lumens will spiral around each other.
- Thrombus will be seen in false lumen
Aortic dissection - true vs false lumen (9)
True lumen:
- has continuity with undissected portion of aorta,
- has smaller cross section with higher velocity of blood,
- surrounded by calcifications if present,
- Usually contains origins of Coeliac trunk, SMA and right renal artery
False lumen
- Cobweb sign, slender linear areas of low attenuation
- Larger cross section, slower blood flow,
- Beak sign
- Usually contains left renl artery origin
- Surrounds true lumen in type A
Intimo-intimal dissection - features (2)
Rare type of dissection, circumferencial dissection of intimal layer, which then invaginates.
Intimal tear usually starts near coronary orifices.
Floating viscera sign (3)
Abdominal aortic dissection.
Opacification of abdominal aortic branch vessels during angiography (catheter in true lumen), with branch vessels (SMA, coeliac axis, renal arteries) arising out of nowhere.
Appear to be floating, with no or little antegrade opacification of the true lumen.
Aneurysm with thrombus vs dissection with thrombus in false lumen (3)
Dissection is spiral shape, thrombus tends to be circumferencial.
Dissection has smooth border, Mural thrombus has irregular border.
Dissection will have displaced calcification
Intramural haematoma - features (3)
Seen on old hypertensives, like dissection.
Spontaneous haemorrage caused by rupture of vaso vasorum in the media, without intimal tear.
Can proceed to classic dissection.
Intramural haematoma - trivia (4)
Still classified as type A or B.
Increased mortality if:
- Ascending aorta >5cm (strongest predictor of dissection)
- IMH >2cm,
- Pericardial effusion.
Intramural haematoma - imaging (3)
Unenhanced CT shows crescent of high attenuation.
Intimal calcifications may be displaced.
MRI: T2 bright blood acutely, T1 and T2 bright blood in subacute phase
Penetrating ulcer - features (4)
Ulceration of atheromatous plaque that has eroded the inner elastic layer of aortic wall.
Produced a haematoma when it reaches the media.
Occurs in older people with underlying severe atherosclerosis.
Can lead to saccular aneurysm.
Penetrating ulcer - trivia (3)
Still A and B classification w/corresponding surgical or medical Rx.
Mortality predictors:
- Ascending aorta >5cm (strongest predictor of dissection),
- IMH >2cm,
- Pericardial effusion.
Aneurysm vs pseudo-aneyrusm (5)
True aneurysm = enlargement of lumen to 1.5x normal.
True = all 3 layers INTACT, false is essentially a contained rupture (carries higher risk of true aneurysm).
Generally: Fusiform aneurysms are true, saccular might be false.
Doppler: Yin-yang sign (to and fro on pulsed doppler in pseudo-aneurysm, can also occur with true, saccular aneurysms).
To and fro within aneurysm neck, plus clinical Hx is bestt way to tell apart.
Causes of pseudo-aneurysm. (5)
Trauma,
Iatrogenic (groin access),
Infection (mycotic),
pancreatitis,
some vasculitides.
SVC syndrome - aetiology (3)
Secondary to complete or near complete obstruction in SVC, caused by:
- external compression (lymphoma, lung Ca) or
- intravascular obstruction (Central venous catheter, pacemaker wire with thrombus)
- fibrosing mediastinitis (think histoplasmosis).
SVC syndrome - clinical (3)
Face, neck, bilateral arm swelling.
Traumatic psuedoaneurysm - trivia (3)
Most commonly in aortic isthmus (90%). Result of tethering from ligamentum arteriosum.
2nd & 3rd commonest are ascending aorta and diaphragmatic hiatus.
Traumatic pseudoaneurysm - imaging (4)
CXR:
- wide mediastinum,
- deviated NG tube to right,
- depressed left main bronchs
- left apical cap