1. Respiratory Cycle & Mechanics Flashcards
what does Vdot mean
airflow or vol per unit time
what happens to RV with age & disease
increases
how does change in volume affect pressure
P1*V1= P2*V2
increase vol -> decrease pressure
what happens during inspiration
passive movement of air into lungs
contract inspiratory Ms - increase thoracic volume
how are the lungs & M/ribs connected
tethered w/ fluid (pleura)
what is parietal fluid
btn visceral & parietal pleura
5-35 um thick
What is PPL
intrapleural P
less than atm P (neg compared to atm P)
=P in thorax (except lumen of blood vessels, lymphatics or airways)
barometric P = 760 mm Hg- how is this converted to P in respiratory phys
0 cm H20
what is PPL at rest
-5 cm
what happens to lungs are the thorax expands
lungs expand bc coupling btn lungs & chest wall
what happens to PPL & PA as thoracic cavity increases in size
PPL = decreases
PA = decreases (causes air to enter during inspiration)
what is transpul pressure
PTP = PALV - PPL
= 5 cm H20 at rest
what is Vol, PA, PPL, PTP & Air flow at rest
Vol = 0 L (only RV, VT hasnt begun)
PA - 0 cm H20
PPL = -5 cm H20
PTP = +5
airflow = 0 L/s
what is Vol, PA, PPL, PTP & air flow during mid-inspiration
Vol - increasing
PA - decreasing (-1)
PPL - decreasing (btn -5 & -8)
PTP = +5.5
airflow - into lungs (neg)
what is Vol, PA, PPL, PTP & air flow at the end of inspiration
Vol - peaked - VT = 500 ml
PA = 0
PPL = decreased to -8 cm H20
PTP = +8
airflow - none
what happens to the diaphragm and chest cavity with expiration
diaphragm relaxes and moves up
chest cavity moves in
PA increases bc recoil
what is Vol, PA, PPL, PTP & air flow during mid-expiration
vol- decreasing
PA - rises
PPL - begins to rise (btn -8 to -5)
PTP = +7.5
airflow - exit lungs (+)
what is Vol, PA, PPL, PTP & air flow at end of respiration
vol- return to resting
PA - decreased back to 0
PPL = at rest = -5
PTP = +5
airflow - none
what is minute ventilation (VE)
vol of air inhaled every min
= VT * Freq
normal = 7 L/min
what is anatomic dead space
space in resp system other than alveoli
take weight and change to mL (150 lb = 150 mL)
what is alveolar dead space
alveoli that recieve air but no blood (no gas exchange)
what is physiological dead space
air that fxnally doesn’t participate in gas exhange
healthy ind = 0

what happens to deadspace at the end of expiration & end of inspiration
end of expiration = air left in lungs (yellow)
end of inspiration = anatomical dead space air entered lungs

what happens if you increase RV too much in alveoli that arent there or fxning correctly
mess w/ gas exchange
increase phys dead space



