1 Powerpoint Flashcards
Aristotle
Thought the heart was the seat of mental capacities, the brains job was to cool the blood.
What’s the neuron doctrine
Brain composed of independent cells. Signals transmitted from cell to cell across gaps.
Hippocrates view?
Wrote of the brain as the seat of thoughts and emotions
Galen
Reported behavioral changes in brain injured gladiators
What’s old phrenology?
Assigned separate functions to cortical areas. Bumps on the skull were thought to overdue enlarged brain regions which were matched to behaviors. “More bumps - smarter”
What’s the neuron doctrine?
Brain composed of independent cells. Signal transmitted from cell to cell across gaps.
Santiago Ramon y cajal
Used golgis cell staining method to observe neurons - proposes neuron doctrine.
Uni polar neurons
A single extension that branches in two directions, forming a receptive pil and an output zone
Bipolar neurons
One axon, one dendrite. Only found in the eye
Multi-polar neurons
One Avon, many dendrites - most common type. Very slow
Input zone
Where neurons collect and integrate information, either from the environment or from other cells
Integration zone
Where the decision to produce a neural signal is made
Conduction zone
Where information can be transmitted over great distances
Output zone
Where the neuron transfers information to other cells
Sensory neurons
Respond to environment, such as light, odor, or touch
Motoneurons
Contact muscles or glands
Interneurons
Receive input from and send input to other neurons - integration (most neurons in CNS)
Name the 4 glial cells
A strictures, oligodendrocytes, ependymal cells, microglia
What’s an astrocytes
Most numerous glial cell in brain, look like star. Fill spaces between neurons for support, regulate composition of the extracellular space. Mainly for support
What’s Alexander’s disease?
Astrocytes fill up w gfap, then fail
Oligodendrocytes
Wrap axons with myelin sheaths inside brain and spinal cord. Each oligodendrocyte wraps several axons. Form segments of myelin sheaths
What’s nodes of ranvier?
Where axon membrane is exposed
What do oligodendrocytes have to do with MS
They are seen as foreign bodies and get attacked. It’s an injury from autoimmune attack
What the function of microglia cells?
Phagocytes that clean up debris from dying neurons and glia
What are ependymal cells function
Line ventricles, secrete and absorb cerebral spinal fluid
What are dendritic spines
Dendritic spines have neural plasticity - their # and structure are rapidly altered by experience ( they increase surface area)
What are the pre ganglionic neurons?
From CNS to autonomic ganglia