1. Organs of the immune system, Natural immunity; The complement system Flashcards

1
Q

Organs of the immune system; Primary what is it made of

A

Thymus
*Bursa (B-equivalents): Embryonic liver Bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Organs of the immune system; secondary what is it made of

A

Lymph nodes
*Spleen
*MALT Mucosa Associated LymphTissue
*GALT Gut Associated LymphTissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Natural immunity: Main molecular components

A

Complement factors and their receptors
o Heat shock proteins
o Fc receptors
o Inflammatory cytokines, histamine,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Natural immunity: Main cellular components

A

Macrophages
o Natural killer cells
o Granulocytes
o Dendritic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Natural immunity:Functional characteristics

A

None antigen specific
o No immunological memory
o Rapid reactivity
o Linear amplification of the reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Natural immunity: humoral factors

A

Complement system
o Lysosin
o C-reactive protein
o Interferon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

The complement system: The cascade is activated in three ways:

A

Classic adaptive pathway
o Natural hereditary alternative pathway:
o MBL: mannose binding lectin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

The complement system: The cascade is activated in three ways: classic adaptive pathway

A

Known antigen-antibody complex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

The complement system: The cascade is activated in three ways: natural hereditary alternative pathway:

A

o unknown antigen appears

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The complement system: The cascade is activated in three ways: MBL: mannose binding lectin

A

Binds oligosaccharides of certain virus/bacteria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The 3 Funtions of the Complement

A
  1. Complement has an intrinsic ability to LYSE bacterial membrane.
  2. Complement initiates CHEMOTAXIS, Complement-factors attract phagocytes to the site of the reaction.
  3. Stimulate OPSONIZATION, facilitating bacterial phagocytosis (resulting in Inflammation)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly