1 Normal Aging Flashcards

1
Q

Art 1

Europe

A

Europe is the oldest continent of the world. Every 6th European is 65+. In 2050 the expectation is that every 4th European will be 65+.

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2
Q

Art 1

Gerontology

A

The study of human ageing. It draws from many scientific disciplines: sociology, economy, psychology, etc.
Gerontology is derived from two Greek words:
- Geron= Old man.
- Gerh= Growing up, maturing or ageing. This means that it refers to being old, and the process of ageing.

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3
Q

Art 1

What is old age?

A

It is not only a biological concept, but also a social concept.
- Society influences how we see ourselves, our opportunities and how our lives are structured as we age.

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4
Q

Art 1

Social and biological concepts

A

For a long time, the social and biological side of age went hand in hand. The age of 65
(which is the age that people retired) was often an age of health problems. This age was a marker of both social and biological old age. However, people now retire earlier and remain healthy until an older age. This means that 65 is now a poor marker for both the biological and the social aspect of old age.

Solution the development of new concepts=
- The third age (the young-old) = A period of freedom and good health.
- The fourth age (the old-old) =
A period of decline of both physical and mental health, the number of losses exceeds the number of gains (het aantal verliezen is groter dan de winsten).

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5
Q

Art1

How old is Europe?

A

Europe is heterogeneous in many respects, and there exists diversity between and within countries. The oldest continent of the world is Europe (median age = 40), followed by Northern America. The youngest continent of the world is Africa. The medium age in Europe is 12 years more than the medium age in the world and 21 years more than the medium age in Africa.
Within Europe, the ageing is divided=
There are different shades of grey within Europe and also within the countries itself. The oldest population in Europe will be the West and the South of the continent, while the North and the East will hold the youngest populations. But these differences now a day are less crisp (minder scherp).
Countries with low median age=
For example; Iceland, Ireland, Albania, Moldova and Turkey.
Countries with median age on an intermediate level=
Sweden and Finland in the North, Germany and the Czech Republic, Italy and Greece. Portugal is an outlier in this group.
The highest medium age in Europe=
Many of these old countries are in Eastern Europe, others are in the North, South or West. Examples; Estonia, Spain, Norway and France.

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6
Q

Art 1

Differences between populations

A

The shades of grey do not stop at the country level. They also exist within countries, because the populations within countries do not age homogeneously. There are marked differences between population groups when it comes to how fast population ageing progresses. These differences originate from differences between population groups: gender, rural/city areas, migration patterns, etc.

For example=
There are more women than men in the higher age groups, and the population in rural areas often ages faster than the population in cities.

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7
Q

Art 1

The ‘older European’ doesn’t exist

A

only a little resemblance between older Europeans, but much more marked differences, due to:

  • Country characteristic (politics, religion, etc.).
  • Differences between individuals (gender, social-economic status, religion affiliation etc.).
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8
Q

Art1

Individual differences

A

-Gender=
There are more women than men 65+.
This is the result of two factors=
- Woman live longer than man.
- Men fought as soldiers during WWII (reduction in the WWII generation of man).
-Social networks=
Social connections enhance well-being, health and support. The modernization had led to a loosening of kinship ties, but in the South and East of Europe, family ties are still very important. In the North, you see extended de-familization (in Scandinavia & Netherlands: highest memberships of clubs and voluntary organizations due to de- familization; meaning that friends and associations become more important).
-Socio-economic status=
A person’s social-economic status describes the position he or she has in society because of wealth, educational level and occupational prestige (rijkdom, educatieve niveau en beroepsmatige prestige).
-The wealth of older Europeans
High in continental countries (Belgium, Switzerland, France) low in east Europe (Poland, Czech Republic).
-The educational level and occupational prestige of Older Europeans
High in Northern and continental countries (Denmark and Austria), low in South Europe (Spain and Greece).
-Health status=
Good in northern countries, worse in the south and east of Europe. These health differences are partly due to life-style, partly to health care systems. Men have a better perceived health (zelf-waargenomen gezondheid), women have longer life expectancies (levensverwachting).
-In general=
The east of Europe has the least favourable circumstances (minst gunstige) with respect to healthy ageing. The west and the north of Europe have the bests circumstances with respect to healthy ageing.
-Country-profile=
First, we will describe Italy, which is one of the oldest countries in Europe. Then, we will look at Sweden, which has an average share of older people for European standards. Finally, we will look at Slovakia, which is one of the youngest countries in Europe.

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9
Q

Art1

Examples of old age in different countries

A

-Old age in Italy=
The second oldest country of Europe (after Germany), and the 3rth oldest country in the world! Italians report that they think old age starts at 68, this is one of the highest reported ages of Europe. Older Italians have low levels of engagement in productive activities, sports, clubs and voluntary organizations. The employment rate of 55-64 old people i9s (2009) the lowest of Europe: 37%. There is a strong engagement in their families. The public care services are scarce and therefore the most care work is done by family or ‘badanti ‘(migrant care workers).
-Old age in Sweden=
Sweden has the highest percentage of older people (55-64) working for pay: 70%. Ageing seems to have only a little e ect on the labour market. Swedes report that they think old age starts at 67. They also live longer than the average European, and stay healthy until a really old age. Swedes are active until a late age and do much volunteer work. They are less active in volunteer organizations. They work until the age of 67.
-Old Age in Slovakia=
Slovakia is one of the youngest countries of Europe. The median age is 37. After the age of 65, only 3 more years in good health are expected. The overall life expectancy lies 3 years below the average of Europe. Slovakians report that they think old age starts at 58. The average retirement is around the same age. Pensioners are less likely to volunteer, but feel nevertheless integrated in society (voelen zich toch geïntegreerd in de samenleving).

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10
Q

Art 2

Definitions

A

Bio- and health gerontology=
Investigates the physical changes during the ageing process.
Aging=
Ageing is a complex process involving biological, social, psychological, environmental and spiritual components. Gerontology is the study of these components and their interrelations, with the subdisciplines bio- and health gerontology focusing on physical processes.
Bio-gerontology=
Focusses on the physical mechanisms of ageing. Studying ageing processes on a molecular level, exploring how the aging processes aspect organs and the entire body.

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11
Q

Art 2

Aubrey de Grey

A

Saw ageing as a disease, and ageing should therefore be possible to be cured. Other biogerontologists see this view of de Grey as too optimistic: no approach has ever been able to extend the life span of any organism. The main criticism of bio-gerontology is that it is a young discipline and therefore still needs a few decades to develop.

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12
Q

Art 2

Health-gerontology

A

Focusses on the health status and health care of older people. Focusses on the health status and health care of older people. It is the scientific field of doctors and epidemiologists. Studying populations cross-sectionally and longitudinally. It is closely linked to the environmental aspects of ageing.
The consequences of bodily changes (because of ageing) on daily living and the use of health care services. It underlines two levels of health-related interventions:
1. The individual level (for example focus on health promotion and disease prevention)
2. The level of populations (focus on poverty prevention, housing conditions and organization of health and social care systems). Both focus on the physical processes of older age and ageing.

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13
Q

Art 2

What is health in old age?

A

Health is the freedom of disease. As individuals age, diseases develop, so old age and good health were seen as mutually exclusive states.
This perception of old age can be explained with senescence=
Describes the process of biological ageing (senescence means that the body reacts more slowly to changes (with the consequence of recovering from diseases becomes more di cult). So: as someone becomes older, health declines and disease becomes more common.
Brody & Schneider: there are two reasons why older people have more health problems:
- Ageing itself causes health to decline.
- Disease requires a longer period of time to develop, so they can only manifest in old ages.
It is important to keep in mind that the presence of disease doesn’t necessarily mean that older people consider themselves in poor health, rather: older people have their own perceptions of their health (subjective).

A more positive approach=
The World Health Organization (WHO) has a broader understanding of old age and health.

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14
Q

Art 2

Health

A

Health=
A state of complete physical, mental and social well-being and not merely the absence of disease or infirmity

The difference with the traditional approach=
It includes also the subjective aspect of social well-being.
But what is social well-being?
Social well-being is closely related to a good quality of life (QoL).
Quality of Life has 2 dimensions=
- A health-related dimension (discomfort, pain, energy level, etc).
- A not-health related dimension (personal resources, as friendships, spiritual satisfaction, etc.) This suggests that there are two ways to maintain a good health in old age:
- Preventing disease;
- Enhancing personal resources.

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15
Q

Art 2

Expanding healthy life-expectancies -> new concepts within old age

A
  • Active ageing=
    The process of optimizing opportunities for health, participation and security in order to enhance QoL.
  • Successful ageing=
    A combination of 3 elements: o The absence of disease;
    o The maintenance of physical and cognitive abilities; o Engagement in productive activities

Both of these concepts underlie productive activities, but there is a difference=
Successful ageing does not draw attention to QoL. Instead, it gives ageing more a normative tone, suggesting that people can also ‘unsuccessfully’ age. Therefore, this term is not very useful.

Conclusion= Healthy ageing focusses on both active ageing and Quality of Life.

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16
Q

Art 2

3 possible ways to age healthy

A
  1. By slowing down ageing processes=
    The process of ageing starts at birth. Adopting a healthy lifestyle at a young age is a central component of this strategy. Also, the use of anti-ageing medicine (without evidence that this works).
  2. By learning from health promoting strategies (good diet, exercise..) =
    The goal of this strategy is reducing the risks leading to one of the following 4 diseases:
    - Cardiovascular disease
    - Lung disease.
    - Diabetes.
    - Cancer.
  3. By utilizing the potentials for preventive medicine.
    Preventive medicine make use of two approaches:
    - Slowing down the ageing process.
    - Learning from health promoting strategies.
    This strategy also places great importance on early diagnosis of disease (early diagnoses can help to ensure good health in old age.
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17
Q

Art 2

Health status of Europeans

A

The health status of Europeans differs widely across the continent.
The highest life expectancies=
The highest life expectancies are seen in the continental, north and south of Europe. The lowest in the East of Europe.
The healthy life expectancies=
The healthy life expectancies are the lowest in Slovakia, and the highest in Sweden.
Capabilities=
When older Europeans were asked whether they were severely limited in their everyday activities, several of them confirmed. Generally speaking, the number of people with limitations in their activities increases with age. When it comes to capabilities, there is no clear geographical pattern like the one in life expectancies.

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18
Q

Art 2

Frailty

A

The state in which people are especially vulnerable to fall ill, have accidents and die prematurely.
Someone is considerate frail when he or she has at least 3 of the following symptoms:
- Unintentional weight loss (4.5 kg in the past year);
- Self-reported exhaustion;
- Weakness (in grip);
- Slow walking speed;
- Low physical activity

There are two lifestyle factors responsible for the development of frailty=

  • Smoking;
  • Lack of physical activity.
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19
Q

Art 2

current leading causes of death

A

The current leading causes of death=
1. Cardiovascular disease;
2. Cancer; 3. Diabetes.
Also, mental health problems can contribute to the cause of death, like depression (possible causes; social isolation, the death of loved ones, health problems and financial problems) and decline in cognitive functioning (dementia).

20
Q

Art 2

Care for frail older Europeans

A

Informal care=
Situations in which individuals provide unpaid care to friends or kin. Usually women provide this care (with the consequence of given women the burden of care and their own life). Luckily, this burden becomes less because women have less children and elderly remain healthy until an older age.
The more north in Europe the more informal care.
In many countries, the older people help out more than they receive help.
- Formal care=
Situations where paid professionals provide care, in institutions or at home. In East Europe, the government spends the least amount of money to health care.

21
Q

Art 2

Is it desirable to live longer?

A

The focus must be on the quality of these additional life years.
There are two competing hypotheses about this question=
- Compression of morbidity=
The most severe health problems are concentrated only in the last years of life. So, living longer means experiencing most of these expanded years in good health, except the last ones.
- Expansion of morbidity=
The number of years that are expanded will be lived in a poor health.

22
Q

Art 2

Hypotheses conclusion

A

Both hypotheses seem to be for a part true.
The most severe health problems indeed seem to be concentrated in the last years of life, while the years before that seem to be concentrated in the last years of life, while the years before that seem to be characterized by chronic diseases which do not necessarily need to lead to disability. People wo can cope with chronic diseases can, therefore, have a pleasant and satisfying old age, even when the life expectancy continues, to expand. With suitable medical care, a well-developed social network, and the right attitude, longer lives can indeed be something to look forward to!

23
Q

Lec

Distribution of ages- population pyramid

A

=Proportion of older adults increases due to increased life expectancy and lower number of children per women

  • Less developed countries have more young people and developed countries are more in one line.
  • The proportion of adults 60+ will increase heavily in the whole world until 2050.
  • The life expectancy at brith will increase in all regions.
  • The number of childern per Women well decrease, also in less developed countries.
24
Q

Lec

Definition of age

A

Chronological age: Measured in units of time that have elapsed since birth (month or years)
Biological age: Where people stand relative to the number of years they will live (in terms of body’s
organ system and physical appearance) = speculative
Functional age: person’s competence in carrying out specific tasks comparing with chronological age
peers.
Psychological age: refers to how well a person adapts to changing conditions
Social age: Views held by most members of society about what individuals in a particular
chronological age group should do and how they should behave.

25
Q

Lec

What is old?

A

Chronological age:
65 is arbitrary (willkührlich) / Young-old: 65-74 / Old-Old: 75-84 / Oldest Old: 85+
Functional age:
Third age: between retirement from work and start of age-impose limitations
Fourths age: cognitive and physical impairments interfering with everyday functioning

26
Q

Lec

Perspectives on aging process

A

Normative aging: what is considered as usual, normal, or average outcome
Successful aging: what is considerd an ideal rather than average outcome
Positive aging: The ability to find happiness and well-bein even in the face of physical and/or
psychological challenges

27
Q

Lec
Theoretical models of aging
1. The selective Optimization with Compensation Model of Aging (Baltes)

A
  1. The selective Optimization with Compensation Model of Aging (Baltes,1990)
    Individuals apapt throughout their lives. They are capable of learning and changing and calling upon
    extra (reserve) capactiy that they might not need to use under ordinary circumstances

Selection: strategy of concentrating efforts on
domains in which effective functioning is most
likely to remain high
Optimization: strategy of focusing on behaviors
that maximize not only the quantity but also
quality of life
Compensation: refers to substituting new
strategies when losses occur.

28
Q

Lec
Theoretical models of aging
2. The Ecological Model of Aging (Lawton, Nahemow, 1973)

A
  1. The Ecological Model of Aging (Lawton, Nahemow, 1973)
    The interaction between a person’s competence
    and environment results in some level of
    adaption (measured in a person’s emotional
    well-being)
    Competence: physical, sensory, cognitive and
    social capabilities
    A person with high competence will adapt
    positively to a wider range of environmental
    press than a person with low competence.
29
Q

Lec

Definitions

A

Aging
Biological changes: Decremental physical change (structural and functional) that develop with the
passage of time and eventually end with death.
Biology of ageing
- Gradual and cumulative (allmählich zunehmend)
- Peak in early adulthood and decline after early adulthood (rate of decline differs strongly
between individuals)
- Not the majority, but even most older adults are neither helpless or dependent
- Aging without disease is rare, the likelihood of disease increases with age
- Aging process and disease process interact!
Morbidity: Refers to illness and disease
Mortality: Refers to death
Illness and disease can result in death. Death is often preceded by illness and disease, Morbidity does
not necessarily result in mortality
Life span: maximum longetivity (extreme upper limit) a species can live (max: 120 years)
Life expectancy: the average number of years that individuals in a particular birth cohort can live
- Increased over time, affected by factors such as nutrition sanitary condition and medical care
- More and more people will approach the maximum life span – compression of mortality!!

30
Q

Lec

Theories of the Biology of Aging

A

Some theories: biological aging occurs within the organism regardless of outside forces
Other theories: biological aging is influenced by our environment and daily habits and the way we
cope with life’s challenges.
Primary aging:
Unavoidable biological prices that affects all members of a species (universal). Begins early in life in
progress gradually over time (individual differences in progression rate). Is intrinsic: determined by
factors within the organism.
Secondary aging:
Experienced by most, but not necessarily all members of a species (neither inevitable nor universal).
Resulting from hostile environmental influences (Disease, Disuse (lack of excersize) and
abuse(smoking).

31
Q
Lec 
Programmed theories (Genetic)
A

Consider aging to be under the control of genetically based blueprint – related to primary aging
Time clock theory:
- Cells doubled 50 times in a human / in a mouse 10-15 times
- Life span is controlled by genetically determined time clock at cellular level
- Cells from infants and young children divide more times than cells from older adults
- There is a protective cap at the tail ends of chromosomes. These shorten and eventually cell
division stops!
Immune theory:
- Immune system: defends body against invasion of foreign substances by producing antibodies
- Theory: Immune system is programmed to maintain its efficiency for certain time, after which
it starts to decline (insufficient antibodies, Inferior antibodies: mistakenly attack and destroy
normal cells, linked to cancer
Evolutionary theory:
- Member of species genetically programmed to bear and rear their young. Once offspring is
produced and raised they have fulfilled their service
- Depending on levels of energy organism coast along for a period of time
- Once excess of energy is used up, susceptibility to disease increases
- Fruit Flies forced to delay reproduction lived longer than fruit flies that reproduced early.

32
Q
Lec 
Stochastic theories (Environment)
A

Focus on random damage to our vital system that occurs with the process of aging – related to
secondary aging. As damage accumulates, we cease to function efficiently and eventually life
becomes impossible to sustain.
Error Rate:
- Error occur at cellular level resulting in the production of faulty molecules (Result from
oganism’s metabolic processes / Exposure to environmental factors (e.g. radiation)
- Cells have a repair mechanism, but may not keep up with damage created by faulty
molecules
- Over time: unrepaired damage builds up resulting into metabolic failure
Wear and tear theory:
- We begin life with fixed amount of physiological energy. If we expend it quickly, ageing begins
early and proceeds rapidly.
- People in tough jobs do NOT show signs of aging any earlier than other jobs!!
Stress theory:
- Tow systems involved (Sympathetic nervous system and Hypothalamic-Pituitary-Adrenal axis)
- Stress triggers physiological activation that results in secretion of stress-related hormones
(glucocorticoids)
- Young organism: stress system quickly return to normal levels
- Older organism: system needs more time to return (Prolonged exposure to glucocorticoids:
Increase risk of high blood pressure and risk of cardiovascular disease)
- Stress-related damage to the biological system can accelerate the aging process

33
Q

Lec

Caloric restriction and longevity

A

Rats consume 50% fewer calories and weigh 50% less than normal rats.
- Lower incidence of cancer, increased longevity
People living in Okinawa have a greater than average longevity (Diet: low in calories, high in
nutrients). People with reduced caloric intake have a lower incidence of some forms of cancer.

34
Q

Lec

Nun study

A

All the same, healthy, education, etc.
Results: striking variability between the sisters
Some: Healthy and active (physical and cognitive) well beyond their ninth decade
Others: confined to wheelchairs and suffered from cognitive impairments due to stroke or dementia
Nurture can not fully account for the rate at which people age and how long they live.
Aging is the result of an interaction between both nature and nurture!!!!

35
Q

Lec

Marital status

A

Married: more likely to have healthy habits such as physical activity, eating breakfast, wearing
seatbelts and abstaining from smoking. (stronger association for men than for women). Older adults
with fewer social contacts were less likely to have healthy habits than those with more social contacts
- Negative effect of martial brakeup
- Single from midlife did not result in greater mortality risk

36
Q

Lec

Maximizing longevity

A

Stop smoking: Decrease risk for cancer and heart disease
Cutting down sugar and fat: reduce risk for some types of cancer and heart disease
Exercise: reduced physical limitations, minimize effects of circulatory disease, contribute to the
maintenance of bone density.

37
Q

Lec

Age-related physical changes

A

First: texture and appearance of skin and hair
- Skin becomes drier, begins to sag and shows wrinkles. Hair becomes thinner and grey
Women vs Men:
Women: facial wrinkles and gray hair need to be avoided
Men: wrinkles are a sign of character and grey hair of distinction

38
Q

Lec

Musculoskeletal system

A

Muscle mass and strength gradually decrease with age. Older adults often take longer to recover
from exertion than younger adults
Reverse capacity of muskuloketal system (as well as of other organ systems) decrease.

39
Q

Lec

Age-related degeneration of joints

A
  • Arthritis: degeneration of joints, cause pain and loss of movement
  • Most common: Osteoarthritis
    o Risk factors: age, obesity, low SES, female gender
    o Cause: wear and tear of time and sometimes injury
    Loss of bone density in the vertabrea:
  • Between 55 and 75
    o Men can lose up to an inch in height, women up to 2 inches
  • Rounding of the back
  • Stooped posture
40
Q

Lec

Osteoporosis

A
  • Extreme loss of bone mass and deterioration of bone tissue
  • Result: bone fragility and susceptibility to fracture
  • Risk factors: age, female, family history, smoking, low vitamine D, inactive lifestyle
41
Q

Lec

Cardiovascular system

A

Diesease:

  • Atherosclerosis
  • Hypertension
  • Aneurysm
  • Stroke
42
Q

Lec
SUMMARY
Age related physical changes

A

Many physical changes occur as people get older. They can interfere with adequate functioning, but
this is not necessarily the case.
Some older adults are more prone to chronic disease than others (Important to screen for risk
factors)

43
Q

Lec

Everyday functioning

A

Activities of daily living (ADL)
Basic self-maintenance tasks: Eating, dressing, toileting, etc
Activities are needed to live independently, ADL assessments are used to determine disability and
need for health-care service, percentage of ADL limitations are much higher among those aged 85+
than its among those aged 65-84.
Instrumental activities of daily living (IADL)
More complex activities required for carrying out daily life: preparing meals, managing money, using
phone, taking medications

44
Q

Lec

Summary

A
  • Proportion of older increases in the next couple of years. Older people can compensate and
    adapt to the aging related changes (including chronic disease) for a long time
  • Biology aging: result of the interaction between genetic and environmental influences
  • Aging is accompanied by a lot of physical changes (skin, hair, mucolokeletal and
    cardiovascular system)
  • To provide good health care several important factors need to be taken into account.
    o QOL, activities of daily living, instrumental activities of daily living.
45
Q

Lec
Causes of Mortality
(Netherlands/Worldwide)

A
The Netherlands 
-Heart disease 
-Cancer 
-Respiratory Disease 
-Psychiatric disorder
-Disease related to digestive system 
Worldwide 
-Heart disease
-Stroke
-Lung infections
-Lung obstruction
-Diarrhea