1. meiosis and genetic variations Flashcards
haploid number of chromosomes
only one copy of each chromosome (this is what gametes have) (23)
diploid number of chromosomes
2 copies of each chromosome (normal body cells) (46)
genetic diversity
- fertilisation is random
- crossing over in meiosis 1 (homologus pairs swap bits of chromatids, exchanging alleles)
- independent segregation
meiosis
start
- DNA unravels and replicates so 2 copies of each chromosome (chromatids)
- DNA condenses to form chromosomes each made from 2 sister chromatids which are joined by centromere
meiosis 1
chromosomes arrange themselves into homogulous pairs
homologous pairs then separate halving chromosome number
meiosis 2
pairs of sister chromatids that make up each chromosome are separate (centromere divided)
4 haploid cells genetically different from eachother produced
independent segregation
homologous pair of chromosomes separated during meiosis 1 random which chromosome from each pair ends up in which daughter cell
4 daughter cells have different combinations of maternal and paternal chromosomes
mitosis vs meiosis
mitosis
1. cells with same number of chromosomes as parent cell
2. daughter cells genetically identical to each other and to parent cell
3. produces 2 daughter cells
meiosis
1. cells with half number of chromosomes as parent cell
2. daughter cells genetically different
3. produces 4 daughter cells
crossing over
meiosis 1
chromatids of homologus pairs cross over / twist around eachother bits of chromatids break off and swap (as in the paternal crosses with maternal)
= different combo of alleles
chromosome mutations
- non-disjunction
failure of chromosomes to separate properly - extra copy of chromosome 21 - down syndrome
- when gamete fuses with another gamete - 3 copies of chromosome 21