1. Intro to the GI System Flashcards

1
Q

What is the alimentary canal?

A

a hallow canal structure that extends from the mouth to the anus

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2
Q

What organs are the alimentary canal composed of?

A

mouth
esophagus
stomach
large intestine
small intestine
liver
pancreas

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3
Q

What is the main processes of the GI tract?

A

digestion
secretion
absorption
excretion

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4
Q

Digestion

A

breaking down food into nutrition

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5
Q

secretion

A

digestive juices are secreted into the digestive tract lumen by exocrine glands (water, electrolytes, enzymes, bile salts or mucus)

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6
Q

motility

A

coordination of contraction of the smooth muscle cells moves secretion contents from the mouth to the anus

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7
Q

Absorption

A

the product of digestion enters the bloodstream via different transports

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8
Q

excretion

A

the undigested food products, bacteria, and certain heavy metal will be released the the rectum and anus

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9
Q

regulation of the GI tract is done by what controls

A

neural
hormonal
paracrine

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10
Q

neural control of the GI tract can be divided into what kind of innervation?

A

parasympathetic (medulla and sacral spine)
sympathetic (thoracolumbar) = extrinsic

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11
Q

extrinsic neurons have cell bodies located where?

A

outside the gut wall innervating the GI tract

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12
Q

intrinsic innervation is referred to as what?

A

little brain

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13
Q

enteric neurons have cell bodies located where?

A

within the walls of the GI tract

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14
Q

what are the principal components of the enteric nervous system (intrinsic innervation)?

A

myenteric plexus = between the layers of the muscularis

submucousal plexus = between submucousa

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15
Q

What are hormones?

A

blood-borne messengers released from endocrine cells into circulation

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16
Q

where are hormones secreted?

A

endocrine glands from sensory and target cells

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17
Q

paracrine control of the GI tract?

A

elicit quicker response than hormonal as they can move through the extracellular matrix via sensory and neighboring cells.

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18
Q

Mouth (saliva)

A

teeth
salivary glands

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19
Q

What are the types of salivary glands and their locations?

A

parotid (in front of the ear)
sub mandibular (below the jaw)
sub lingual (underneath the jaw)

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20
Q

what nerve increases the volume of saliva?

A

parasympathetic

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21
Q

salivation is stimulated by what kind of stimulus?

A

taste
sight
smell
thought

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22
Q

what are the 2 types of receptors that help with saliva secretion?

A

chemical
mechano

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23
Q

saliva is composed of what?

A

99% water

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24
Q

what is the pH of saliva?

A

6.7-7.3

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25
what is the purpose of saliva in the esophagus?
to neuralize gastric secretion
26
another word for deglutition
swallowing
27
what are the 3 phases of deglutition?
oral pharyngeal esophageal
28
what delimits the esophagus
upper and lower sphincter
29
What is prohibited in the esophagus?
air gastric acid
30
what is the stomach's main role?
to secrete digestive juices and break down food and pass it to the small intestine
31
what are the parts of the stomach's structure
cardia corpus pylorus
32
What is the function of the cardia?
first part of the stomach that is connected to the esophagus it contains the cardiac sphincter
33
what is the major part of the stomach
the corpus
34
what is the role of the fundus
to store gas from digestion and hold food when the stomach is full
35
what do gastric glands contain
parietal and chief cells (inside the corpus)
36
what is the pylorus?
the distal part of the stomach that secretes the hormone gastrin from the G cells, and regulates the entry of food from the stomach to the duodenum
37
what are the main gastric gland cells
Mucous cells parietal cells chief cells Endocrine Cells
38
What is the function of mucous cells
to secretes mucus around the stomach lining
39
What is the function of parietal cells
secrete HCl/gastric acid and intrinsic factor for B12 absorption
40
What is the function of chief cells
secrete pepsinogen to form pepsin
41
What is the function of endocrine cells
(D and G cells) release serotonin, histamine, somatostatin, and gastrin
42
What phase prepares the stomach for digestion?
cephalic
43
What is the largest gland in the body
liver
44
what are the lobe of the liver
right left caudate quadrate
45
what is the functional unit of the liver
hepatocyte
46
what is the hepatic sinus
vascular channels that separate the hepatocytes
47
The portal triad of the liver does what
the hepatic artery supplies oxygen portal vein brings nutrient-rich blood bile ducts receives the bile
48
the liver plays a role in what 2 major functions
carbohydrate metabolism (glucose buffer) fat metabolism (oxidize fatty acids)
49
what breaks down bacteria as the liver detoxifies the body
kupffer cells
50
what helps metabolites secrete into bile for elimination
cytochrome P450 enzymes
51
what organ is responsible for the handling of ammonia
the liver
52
how is ammonia exreted
converted to urea, and processed the urea cycle, and excreted as urine
53
what is the only major class of plasma proteins not synthesized by the liver
immunoglobulins
54
What is the function of the large intestine
absorb water, electrolytes, and form feces home of the intestinal microbes
55
what hormone plays an important roles in maintaining fluid and electrolyte balance
aldosterone
56
What is the main phase of acid secretion
gastric, last 3-4 hours
57
Secretion is induced by stimuli within what receptors
stretch
58
food in the stomach triggers
vasovagal reflexes (Ach) and gastrin secretion
59
chief cells secrete what
pepsinogen
60
parietal cells contain what type of pump?
proton potassium pump
61
parietal cells release what
protons
62
where are 90% of nutrients absorbed
small intestine
63
what is the largest part of the digestive system
small intestine
64
what are the 3 parts of the small intestine
duodenum jejunum illeum
65
what is the most important structural feature of the small intestine
villi (entrocyte 3000-5000)
66
what happens with the small