1- Intro & General Principles Flashcards
Define physiology
The science of life- a broad science which aims to understand the mechanisms of living from molecular basis of cell function to integrated behavior of the whole body, it is the study of how the human body works under normal conditions
Regarding medical physiology, what is critical care medicine
It is basically the application of physiologic principles to the care of seriously ill patients
Define homeostasis
It is a regulated process by which a biological system maintains dynamic but relatively consistent internal conditions during pressures incurred from both internal and external factors
Explain the control and regulation process
An external stressor occurs which is sensed by a sensor, the data is relayed to integrator and coordinating center, the control signal is sent to an effector which causes alterations in the regulated variable
List the level of organization
Atom-molecule-macromolecule-organelle-cell-tissue-organ-organ system-organism
Example: control system for arterial blood pressure
Sensors:
Aortic arch baroreceptors via CN X.
Carotid sinus baroreceptors via CN IX.
Integrator:
Nucleus tracts solitarus (medulla)
Coordinating center: Vasoconstrictor Cardiac accelerator (Sympathetic) Cardiac decelerator (Parasympathetic)
Effectors:
Vasoconstrictor to veins & arterioles (blood vessels)
Cardiac accelerator to contractility and SA nodes (heart)
Cardiac decelerator to SA node (heart & blood vessels)
What effect would aging and atherosclerosis have on carotid baroreceptors?
They can blunt baroreceptor responses due to stiffening of the vascular wall not allowing as much transduction of wall distension