1. Intro And Definitions Flashcards
Physiology
Study of normal functions and processes of living organisms
Pathology
Study of cellular abnormalities
Pathophysiology
Study of disordered physiological processes associated with disease or injury
Etiology
Cause
Pathogensis
Sequence of events that lead to disease
Clinical features
Signs/symptoms
Morphological changes
What happens in organ/tissue
Four components of disease Pathophysiology
Etiology
Pathogenesis
Clinical features
Morphological changes
Genetic Etiology
Inherited mutations, disease associated
Acquired Etiology
Infectious
Nutritional - vitamin deficiency
Chemical - smoking
Physical - repeated mechanical stress (carpal tunnel)
Pathogenesis
Sequence of biochemical and molecular events that follow the exposure of cells or tissue to an infectious agent
Clinical features of pathogenesis
Injury to cells extra cellular matrix ultimate leads to tissue and organ injury which determines the morphological and clinical patterns of disease
Sign
Objective evaluation - BP, HR
Symptom
Subjective evaluation - pain, fatigue
Clinical course
Is it fatal? In acute phase?