1. homeostasis Flashcards
what is physiology
study of how the body functions
what is homeostasis
the ability to maintain relatively stable conditions in the internal environment (despite changes in external environment)
*cells can only survive within a narrow range of conditions, therefore body conditions must be maintained within physiological limits
homeostasis conditions controlled include
1) pH
2) temperature
3) blood gases (CO2, O2)
4) blood pressure (b.p.)
5) intracellular + extracellular (ICF +ECF) fluid volumes
6) etc.
what functions together to maintain homeostasis
organ systems
disease =
the failure to maintain homeostasis
nervous and endocrine systems control all other systems (control centers): act to:
1) maintain homeostasis
2) permit departures from homeostasis in a controlled manner
* eg. pregnancy, growth, sudden fright
homeostasis regulation
change in internal environment must be detected or anticipated
*the NS and or endocrine respond alternating systems responsible for that condition
Types of endocrine resposonses
1) anticipatory responses
2) feedback mechanisms
anticipatory responses
*e.g. ⇑ respiratory rate at start of exercise ⇒ proprioceptors (NS sensory
receptors) signal movement before a change in internal conditions (gases
in blood)
* may also be learned or behavioral
(e.g. put on coat)
feedback mechanisms
- mechanisms that respond to change in system
- consist of set points, receptors, control areas, and effectors
- Set point = range of values of a variable (e.g. body temp.) that do not bring
about a response (i.e. “normal range”) - Variable is monitored by receptors ⇒ info (input) fed back to control area (NS/endocrine gland) ⇒ controls the effector (output)
types of feedback mechanisms
negative feedback
positive feedback
Negative Feedback
- Most common homeostatic control mechanism
- Result of “output” W variable moves back toward the set
point i.e. in opposite (negative) direction to the change that
triggered the response (“input”) - e.g. #1: body temp. (= variable) set point 36 to 37.8 oC. If ⇑
temp (e.g. 40 oC): - Result = core blood to skin surface and sweat evaporates = ⇑ heat loss & ⇓ temp (opposite direction of input)
- e.g. #2: ⇓ temp -> shiver -> ⇑ temp
*set point can change e.g fever
positive feedback
- Less common W NOT homeostatic ! Output intensifies the input
- e.g. Childbirth – labour
- check notes for diagrams
- — *continues until endpoint (=baby born)