1. Genome Projects and Sequencing

Question 1

define a genome

Answer 1

a set of all an organisms genetic information

Question 2

what are genome projects

Answer 2

projects which use technology to determine the complete DNA base sequence of an organism

Question 3

list reasons for gene technologies uses over the years

Answer 3

• helps us identify genes associated with certain diseases
• helps us understand inherited disorders
• helps us understand evolutionary relationships between species when creating phylogenetic trees

Question 4

what is proteome sequencing

Answer 4

using technology in order to determine an organisms proteome which has been coded for by the DNA

Question 5

what organisms can proteome sequencing be used on?

Answer 5

bacteria and viruses
- humans it is harder due to the fact that 98.5% of our proteomes are introns, and not exons

Question 6

list the uses of proteome sequencing

Answer 6

• helps us identify antigens of viruses and produce more effective treatment
• helps us recognise variables of diseases

Question 7

briefly outline cycle sequencing

Answer 7

1. DNA fragments are aligned alongside larger ones
2. they are marked with florescent markers
3. they are run through gel electrophoresis, in a single narrow tube
4. it is then read by a laser beam