1/8 Weller Intro to Virology

Question 1

What category of microorganisms are obligate intracellular parasites?

Answer 1

Viruses

Question 2

Types of capsid structure

3

Answer 2

Helical
Icosahedral
Complex (spider looking thing)

Question 3

VIral components

2

Answer 3

Protein covering

Genetic material

Question 4

TYpes of protein covering

2

Answer 4

Envelope

Capsid

Question 5

Types of genome in virus

Answer 5

Group 1
2
3
4
5

Question 6

Group 1

Answer 6

1) DNA +/-

2) mRNA

Question 7

Group 2

Answer 7

1) DNA +
2) DNA +/-
3) mRNA

Question 8

Group 3

Answer 8

1) RNA +/-

2) mRNA

Question 9

Group 4

Answer 9

1) RNA +
2) RNA -
3) mRNA

Question 10

Group 5

Answer 10

1) RNA -

2) mRNA

Question 11

Group 6

Answer 11

1) RNA +
2) RT
3) mRNA

Question 12

Group 7

Answer 12

1) DNA +/-
2) RT
3) mRNA

Question 13

Viral genome types of structure of genome

Answer 13

Linear
Circular
Segmented
Gapped

Question 14

Viral life cycle

Answer 14

Attachment
Entry
Penetration

Question 15

What is the period when the virus is inside the host cell and off the radar of immune system called?

Answer 15

Eclipse face

Question 16

TYpes of enveloped penetration

Answer 16

Fusion

Viropexis (vesicle goes in)

Question 17

How does capsid penetration happen?

Answer 17

Clathrin - mediated endocytosis

Question 18

Susceptibility def

Answer 18

Whether cell has receptors for virus to gain entry

Question 19

Permissivity

Answer 19

Whether cell has machinery to support virus

Question 20

Resistant def

Answer 20

CEll is missing either receptors or machinery or both

Question 21

Cell must be what in order to become infected by virus

Answer 21

susceptible and permissive

Question 22

For DNA viruses, if replication occurs in cytoplasm, then what?

Answer 22

All replication machinery will have to be provided by virus

Question 23

Does +RNA enter the nucleus?

Answer 23

no need

Question 24

-RNA brings what into a cell and why?

Answer 24

RNA reverse polymerase to make complimentary +RNA

Question 25

-RNA replicates in nucleus or cytoplasm?

Answer 25

Either

Question 26

Retrovirus def

Answer 26

RNA viruses that reprodue through DNA intermediate

Question 27

Reverse Transcriptase def

Answer 27

Enzymes capable of making DNA from RNA.

DNA then is integrated into host DNA

Question 28

How is the virus assembled?

Answer 28

In a way to favor incorporation of viral genomes

Question 29

WHat has an impact on mutation rate

Answer 29

Genome Size
Replication Rate
host COnditions

Question 30

In regards to mutation, what has the highest rate of mutation

Answer 30

Smaller size