1/26 Durrant SSTI Flashcards

1
Q

What is the body’s first line of defense?

A

Intact skin

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2
Q

Folliculitis Def

A

Infection associated with sweat glands

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3
Q

WHat causes folliculitis

2

A

S. Aureus

Pseudomonas Aeruginosa

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4
Q

Folliculitis treatment

A

Soap & Water

Topical antibiotics

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5
Q

Acne def

A

Inflammation of hair follicle and sebaceous gland

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6
Q

What causes acne?

A

Proprionibacterium acnes

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7
Q

Whats the most common pathogen of soft tissue abscesses?

A

S. Auereus

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8
Q

Treatment for Soft tissue abscesses

A

Incission & Drainage

Systemic Antibiotics

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9
Q

Types of Soft Tissue abcesses

A

Furuncle

Carbuncle

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10
Q

Furuncle def

A

Abscess in area of hair follicle

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11
Q

Carbuncle def

A

Multiloculated abcess with spread to subcutaneous tissue

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12
Q

Necrotizing Fasciitis Def

A

Enzyme producing bacteria digest fascial barriers

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13
Q

Necrotizing fasciitis causeng pathogens?

A

Group A Strep
Staph Aureus
Clostridium perfringens

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14
Q

What is fournier’s Gangrene?

A

Polymicrobial infection of the genitals involving necrotizing fasciitis

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15
Q

Biggest symptom of necrotizing faciitis

A

Pain is out of proportion compared to exam findings

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16
Q

Mosto common pathogen in surgical wounds

A

S. Aureus

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17
Q

Best way to prevent surgical wound infections?

A

Perioperative antibiotics

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18
Q

Fungal infections are scientifically called

A

Dermatophyte fungi

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19
Q

Fungal nail infections are called

A

Onychomycosis

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20
Q

What genres cause fungal infections

A

1) Trichophyton
2) Microsporum
3) Epidermophyton

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21
Q

Most common yeast pathogen

A

Candida albicans

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22
Q

Treatment against fungal infections

A

Topical antifungals

Systemic antifungals if severe

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23
Q

Diaper rash casued by?

A

yeast

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24
Q

intertrigo casued by

A

Fungus

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25
Q

Thrush casued by?

A

Yeast

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26
Q

Impetigo infects what layer of skin?

A

Epidermis

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27
Q

Impetigo definition

A

Honey Crust

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28
Q

What pathogens casue Impetigo?

A

Group A Strep

S. Aureus

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29
Q

Treatment of impetigo

A

Penicillin

Topical antibiotic

30
Q

Erysipelas infects what layer of skin?

A

Deep layers of dermis

31
Q

What pathogen causes erysipelas?

A

Group A Strep

32
Q

Treatment for Erysipelas

A

Penicillin

33
Q

Cellulitis infects what layer of skin

A

Subcutaneous

34
Q

What pathogen causes Cellulitis

A

Group A Strep

S. Aureus

35
Q

Treatment for cellulitis

A

Systemic antibiotics

36
Q

What factors increase risk of wound infections

4

A
  • Higher num of organisms
  • Higher virulence
  • Poor circulation near wound
  • Poor overall health
37
Q

What type of lesions does staphylococcus aureus create

A

purulent lesions

38
Q

Staphylococcal Toxins

4

A

1) Alpha toxin
2) Exfoliatin
3) TSST -1
4) Enterotoxn

39
Q

Enterotoxin effect

A

Staphylococcal food poinoning

40
Q

TSST - 1 Effect

A

Toxic shock syndrome

41
Q

Exfoliatin effect

A

bullous impetigo

42
Q

alpha -toxin effect

A

Scalded skin syndrome

43
Q

What do beta lactams target on S. Aureus?

A

Peniccilin binding proteins (PBP)

44
Q

MRSA has what gene that makes new PBP with less affinity for beta lactams?

A

mecA Gene

45
Q

MRSA is resistant to what beta lactams?

A

All of them!

46
Q

Treatment for MRSA

A

DOxycycline, Vancomyacin, trimethoprim-sulfa

47
Q

Risk factors for MRSA

A

Skin-skin contact
IV drug use
Crowded living conditions

48
Q

Other name for GRoup A Strep

A

Strep Pyogenes

49
Q

Post strep sequelae

3

A

1) Pharyngitis
2) Rheymatic fever
3) Glomerulonephritis

50
Q

Strep Toxins

2

A
  • Steptolysins O and S

- Pyrogenic exotoxins A and B

51
Q

Strep Inflammatory ENzymes

3

A

1) Streptokinase
2) Hyaluronidase
3) DNAse

52
Q

Clostridium Perfringens Gram Stain

A

Gram Positive

53
Q

C. Perfringens oxygen use

A

anaerobic

54
Q

C. perfringens shape

A

rods

55
Q

C. Perfringens produces what in tissue?

A

Hydrogen and CO2 gas

56
Q

Soft tissue infection caused by C. Perfringens

A

Gas gangrene

57
Q

Pasteurella Multocida gram stain

A

GN Rod

58
Q

Where do you get Pasteurella Multocida?

A

Animal Bites

59
Q

Pseudomonas aeruginosa gram stain

A

GN Rod

60
Q

P. aeruginosa is found where?

A

Environment, Water & hospital rooms

61
Q

What causes hot tub folliculitis?

A

P. Aeruginosa

62
Q

Vibrio vulnificus gram stain

A

GN Rod

63
Q

What disease is associated with an iron overload and cirrhosis?

A

Vibrio vulnificus

64
Q

What casues Mycetoma?

A

Bacterial: actinomyces nocardia
Fungal: many molds

65
Q

What casues sporotrichosis?

A

Sporotrhrix Schenckii

66
Q

What is sporotrichosis common name?

A

Rose gardner’s thumb (bc patches in a row like a garden)

67
Q

How to get a microbiologic diagnosis?

A

Often clinical

Pus!

68
Q

Abscess of skin - think?

A

S. aureus

69
Q

Abscess in mouth, rectum, vagina think?

A

polymicrobial

70
Q

Cellulitis think?

A

S. pyogenes

71
Q

Erysipelas think?

A

S. pyogenes

72
Q

exposure to IV in drug user think?

A

pseudomonas