1

Question 1

types of cholinergic receptors

Answer 1

muscarinic

nicotinic (faster response compared to muscarinic)

Question 2

name some cholinomimetics

Answer 2

cholinergic receptor agonists
-acetylcholine (ACh)
- muscarinic and nicotinic ACh
-choline ester (have selectivity for Nic or Musc)
cholinesterase inhibitors

Question 3

choline ester cholinomimetics

Answer 3

• bethanechol

- succinylcholine

Question 4

bethanechol

Answer 4

choline ester cholinomimetics

• muscarinic receptor selective
• uses: GI and UB atony (lack of muscle strength)

Question 5

succinylcholine

Answer 5

choline ester cholinomimetics

• nicotinic (NM) receptor selective
• uses: muscle relaxant (no contraction; cause paralysis in all muscles)

Question 6

non choline ester, cholinomimetics

Answer 6

• varenicline

- pilocarpine

Question 7

varenicline

Answer 7

non choline ester, synthetic cholinomimetics

• uncharged
• nicotinic NN receptor selective
• uses: nicotine addiction (prevent nicotine binding; help smokers)

Question 8

pilocarpine

Answer 8

non choline ester, non synthetic cholinomimetics

• uncharged
• muscarinic receptor specific
• uses: glaucoma (retina damaged), xerostomia (mouth dryness; stimulate saliva secretion)
• CAUTION: not recommended (cardiac, blood vessel and bronchiole,and CNS effects)

Question 9

nicotine

Answer 9

non choline ester, non synthetic cholinomimetics

• uncharged
• nicotinic receptor specific
• uses: nicotine addiction, insecticide