09 Fluids & Electrolytes {Pathophysiology} Flashcards

0
Q

Each compartment in the body has a particular composition of electrolytes, which differs from that of their compartments. To function normally, ______ _______ must have fluids and electrolytes in the right compartments and in the _____ ______.

A

body cells

right amounts

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1
Q

Whenever an electrolyte moves out of a cell ___________.

A

another electrolyte moves in to takes its place.

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2
Q

The number of cations and _______ must be ______ to have _______.

A

The number of cations and anions must be the same to have homeostasis to exist.

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3
Q

Intravascular compartment

A

fluid inside a blood vessel

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4
Q

Intracellular compartment

A

all fluid inside the cell

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5
Q

Most body fluids are

A

inside the cells

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6
Q

Extracellular compartments are

A

the interstitial fluid (fluid BETWEEN cells) often called third space, blood, lymph, bone, connective tissue, water and transcellular fluid

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7
Q

Third spacing

A

the accumulation and sequestration of trapped extracellular fluid in an actual or potential body space as a result of disease or injury; considered a volume loss and is unavailable for normal physiological processes

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8
Q

Edema

A

an excessive accumulation of fluid in the interstitial space; occurs as a result of alterations in oncotic pressure, hydrostatic pressure, capillary permeability and lymphatic obstruction

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9
Q

localized edema

A

occurs as result of traumatic injury for accidents or surgery, local inflammatory processes or burns

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10
Q

generalized edema (also called anasarca)

A

is the result of extra fluid throughout the body and is a result of conditions such as cardiac, renal, or liver failure

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11
Q

Total body fluid (intracellular and extracellular)

A

60% of weight in adult
55% in older adults
80% in infants

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12
Q

Who is at higher risk for fluid related problems?

A

infants and older adults due to their higher and lower percentages of body fluids

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13
Q

Osmotic pressure

A

a pull that draws water through a membrane to a more concentrated side, or side with more solute; it is caused by this imbalance in solutes

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14
Q

filtration

A

the movement of solutes and solvent by hydrostatic pressure

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15
Q

hydrostatic pressure

A

the force exerted by the weight of a solution

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16
Q

At the ______ ______ of the capillary, the hydrostatic pressure is _______ than the osmotic pressure; therefore fluids and diffusible solute move _____ of the capillary.

A

arterial end
higher
out

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17
Q

At the _______ ______, the osmotic pressure or _____, is higher than the hydrostatic pressure and fluids and some solutes move _______ the capillary.

A

venous end
pull
out

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18
Q

What happens to the excess fluid and solutes taht remain in teh interstitial space?

A

They are returned to the interstitial space by the lymph channels.

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19
Q

Osmolality

A

the number of osmotically active particles per kilogram of water; also known as the concentration of a solution

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20
Q

What is the normal osmolality of plasma?

A

270-300 milliosmoles/kg (mOsm/kg)

21
Q

What happens with an individual has diarrhea?

A

the body loses more electrolytes that it does fluids and it creates an environment where the extracellular fluid contain fewer electrolytes or less solutes than he intracellular fluid

22
Q

The thing to remember about electrolyte/solute equilibrium

A

fluids and electrolytes must be kept in balance for health; when they remaine out of balance, death can occur

23
Q

isotonic solutions

A

the solution on both side of a selectively permeable membrane have established equilibrium or have an equal concentration; very little osmosis will occur

24
hypotonic solutions
when a solution contains a lower concentration of salt or solution than another solution hypotonic solutions have fewer solutes than the cell so osmosis or the pulling in of the solution into the cell would occur
25
hypertonic solutions
a solution that has a higher concentration of solutes than another, less concentrated solution; have a higher osmolality than body fluids a hypertonic solution would draw fluid out of the cells and into the interstitial or vascular space
26
osmotic pressure
the amount of osmotic pressure is determined by the concentration of solutes in solution
27
A ________ solution has less solutes than the cells A ________ solution has more solutes than the cells A ________ solution has the same amount of solutes as the cells
hypotonic hypertonic isonoinc
28
Substance that are moved through active transport
sodium potassium calcium
29
the amount of water released by metabolism of each 100 calories of fat, carbohydrates, or protein
10 mL of water
30
insensible water loss
loss through skin (about 100 mL per day) | loss from the lungs (varies)
31
water balance related to the gastrointestinal tract
large quantities of electrolyte-containing liquids are secreted into the GI tract but almost all of this fluid is reabsorbed unless there is severe diarrhea; in this case large quantities of fluid and electrolytes are lost
32
kidneys
play a major role in regulation of fluids and electrolytes and excrete the largest amount of fluids; normal kidneys can adjust the amounts of water and electrolytes leaving the body
33
adrenal glands in fluid volume homeostatis
the adrenal glands (that sit atop the kidneys) secrete aldosterone which aids in the control of extracellular fluid volume by regulating the amount of sodium that is reabsorbed by the kindneys (look up more info on this!!)
34
the effect of the pituitary gland (located in the brain) on fluid homeostasis
the pituitary gland regulates the osmotic pressure of extracellular fluid through the release of antidiuretic hormone that helps in the regulation of the amount of water that is reabsorbed by the kindneys`
35
What is the GOAL of TX in fluid volume deficient?
to restore fluid volume, replace electrolytes as needed and eliminate the cause of the fluid volume deficit
36
Three types of fluid volume deficit
isotonic dehydration hypertonic dehydration hypotonic dehydration
37
isotonic dehydration
water and electrolytes are lost in equal proportions it is known as hypovolemia and is the most common type of dehydration results in decreased circulating blood volume and inadequate tissue perfusion
38
hypertonic dehydration
water loss exceed electrolyte loss (the serum osmolality is too high) problems occur from alteration in concentration of specific electrolytes moves from the intracellular compartments into the plasma and interstitial fluid spaces causing the cells they be dehydrated and shrink
39
hypotonic fluid volume deficits
electrolytes exceed water losses (to few electrolytes) clinical problem occur as a result from fluid shifts between compartments, causing a decrease in plasma volume fluid moves from the plasma and interstitial space into the cells, causing a plasma volume deficit causing cells to swell
40
causes of isotonic dehydration
inadequate intake of fluids and solutes fluid shifts between compartments excessive losses of isotonic body fluids
41
causes of hypertonic dehydration
conditions that increase fluid loss; excessive perspiration, hyperventilation, ketoacidosis, prolonged fevers, diarrhea, early-stage kidney disease and diabetes insipidus
42
causes of hypotonic dehydration
chronic illness excessive flid replacement (hypotonic) kidney disease chronic malnutrition
43
In general isotonic dehydration is treated with _________ fluid solutions, hypertonic dehydration is treated with _______ fluid solutions and hypotonic dehydration is treated with _______ fluid solutions.
isotonic hypotonic hypertonic
44
Fluid volume excess is also called
overhydration or fluid overload
45
Types of fluid volume excess
isotonic overhydration (known as hypervolemia) hypertonic overhydration hypotonic overhydration
46
isotonic overhydration
known as hypervolemia is excessive fluid in the extracellular fluid compartment; shifting does not occur and it causes circulatory overload and interstitial edema; pulmonary edema may occur
47
hypertonic overhydration
is rare and is caused by excessive sodium intake; fluid is drawn from the the intracellular fluid compartment; the extracellular fluid volume expands and the intracellular fluid volume contracts
48
hypotonic overhydration
also known as water intoxication; excessive fluid moves into the intracellular space, and all body fluid compartments expand; electrolyte imbalances happens as a result of dilution
49
causes of isotonic overhydration
inadequately controlled IV therapy kidney disease long-term corticosteroid therapy
50
causes of hypertonic overhydration
excessive sodium ingestion rapid infusion of hypertonic saline excessive sodium bicarbonate therapy
51
causes of hypotonic overhydration
early kidney disease heart failure syndrome of inappropriate antidiuretic hormone secretion inadequately controlled IV therapy replacement of isotonic fluid loss wit hypotonic fluid loss irrigation of wound and body cavities with hypotonic fluids